5-Methyluridine-d4

Modify Date: 2024-01-14 22:37:57

5-Methyluridine-d4 structure	Common Name	5-Methyluridine-d4
	CAS Number	82845-85-0	Molecular Weight	262.25300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₀D₄N₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-Methyluridine-d4

5-Methyluridine-d4 is the deuterium labeled 5-Methyluridine[1]. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids[2].

Name	6-deuterio-1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trideuteriomethyl)pyrimidine-2,4-dione
Synonym	More Synonyms

Description	5-Methyluridine-d4 is the deuterium labeled 5-Methyluridine[1]. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids[2].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Yang TH, et al. Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55(2):224-31.

Molecular Formula	C₁₀H₁₀D₄N₂O₆
Molecular Weight	262.25300
Exact Mass	262.11000
PSA	124.78000

5-Methyl Uridine-d4