Apocynin-d3
Modify Date: 2024-01-06 18:41:22
Apocynin-d3 structure
|
Common Name | Apocynin-d3 | ||
|---|---|---|---|---|
| CAS Number | 80404-23-5 | Molecular Weight | 166.17400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H10O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Apocynin-d3Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4]. |
| Name | 1-[4-hydroxy-2-(trideuteriomethoxy)phenyl]ethanone |
|---|---|
| Synonym | More Synonyms |
| Description | Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
[2]. Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102. |
| Molecular Formula | C9H10O3 |
|---|---|
| Molecular Weight | 166.17400 |
| Exact Mass | 166.06300 |
| PSA | 46.53000 |
| LogP | 1.60340 |
|
~22%
Apocynin-d3 CAS#:80404-23-5 |
| Literature: CONCERT PHARMACEUTICALS INC. Patent: US2008/255194 A1, 2008 ; Location in patent: Page/Page column 12 ; US 20080255194 A1 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| Acetoguaiacon-d3 |
| Apocynine-d3 |
| 1-(4-hydroxy-3-(d3)methoxyphenyl)ethanone |
| Acetoguaicone-d3 |
| 2-Methoxy-4-acetylphenol-d3 |
| Acetovanillone-d3 |
| 4-Acetyl-2-methoxyphenol-d3 |
| Apocynin-d3 |
| 4-Acetylguaiacol-d3 |
| Acetoguaiacone-d3 |