thromboxane A2

Modify Date: 2024-01-02 12:19:24

thromboxane A2 structure	Common Name	thromboxane A2
	CAS Number	57576-52-0	Molecular Weight	352.46500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₃₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of thromboxane A2

Thromboxane A2 (TXA2) is a prostanoid mediator produced by the metabolism of Arachidonic acid (HY-109590) through the cyclooxygenase pathway. Thromboxane A2 activates the thromboxane-prostanoid (TP) receptors. Thromboxane A2 is a potent vasoconstrictor eicosanoid. Thromboxane A2 (TXA2) leads to potent vasoconstriction by stimulation of smooth muscle cells. Thromboxane A2 acts as s tonic immunoregulator to regulate adaptive immune responses[1][2].

Name	thromboxane A2

Description	Thromboxane A2 (TXA2) is a prostanoid mediator produced by the metabolism of Arachidonic acid (HY-109590) through the cyclooxygenase pathway. Thromboxane A2 activates the thromboxane-prostanoid (TP) receptors. Thromboxane A2 is a potent vasoconstrictor eicosanoid. Thromboxane A2 (TXA2) leads to potent vasoconstriction by stimulation of smooth muscle cells. Thromboxane A2 acts as s tonic immunoregulator to regulate adaptive immune responses[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
Target	Human Endogenous Metabolite TP
References	[1]. Matthew A Sparks, et al. Thromboxane receptors in smooth muscle promote hypertension, vascular remodeling, and sudden death. Hypertension. 2013 Jan;61(1):166-73. [2]. Federica Moalli, et al. Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4+ T cell-dendritic cell interactions. J Exp Med. 2014 Dec 15;211(13):2507-17.

Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.46500
Exact Mass	352.22500
PSA	75.99000
LogP	3.81500

thromboxane A2

Use of thromboxane A2

Names

thromboxane A2 Biological Activity

Chemical & Physical Properties