N-Methyl(N-2H)acetamide

Modify Date: 2025-08-20 13:46:36

N-Methyl(N-2H)acetamide Structure
N-Methyl(N-2H)acetamide structure
Common Name N-Methyl(N-2H)acetamide
CAS Number 3669-70-3 Molecular Weight 74.100
Density 0.9±0.1 g/cm3 Boiling Point 206.0±0.0 °C at 760 mmHg
Molecular Formula C3H6DNO Melting Point N/A
MSDS N/A Flash Point 108.3±0.0 °C

 Use of N-Methyl(N-2H)acetamide


N-Methylacetamide-d1 is the deuterium labeled N-Methylacetamide[1].

 Names

Name n-methylacetamide-n-d1
Synonym More Synonyms

 N-Methyl(N-2H)acetamide Biological Activity

Description N-Methylacetamide-d1 is the deuterium labeled N-Methylacetamide[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 206.0±0.0 °C at 760 mmHg
Molecular Formula C3H6DNO
Molecular Weight 74.100
Flash Point 108.3±0.0 °C
Exact Mass 74.059044
PSA 29.10000
LogP -1.05
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.383

 Synthetic Route

~%

N-Methyl(N-2H)acetamide Structure

N-Methyl(N-2H)a...

CAS#:3669-70-3

Literature: Reuben, Jacques Journal of the American Chemical Society, 1986 , vol. 108, # 5 p. 1082 - 1083

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

N-methylacetamide-d3
Acetamide,methyl
N-Methyl acetamide
Acetylmethylamine
N-Methyl-C-trideutero-acetamid
N-Deuterio-N-methyl-acetamid
2,2,2-trideuterio-N-methyl-acetamide
Acetamide-d, N-methyl-
Acetamide,N-methyl
N-methylacet-d3-amide
N-methylacetamide-N-d
N-acetylmethylamine
methyl acetamide
Monomethylacetamide
N-methylacetamide-d
N-deuterated N-methylacetamide
N-deuterio-N-methyl-acetamide
N-Methyl(N-H)acetamide
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