Estrogen receptor modulator 10

Modify Date: 2025-10-10 19:34:20

Estrogen receptor modulator 10 Structure
Estrogen receptor modulator 10 structure
Common Name Estrogen receptor modulator 10
CAS Number 2991504-90-4 Molecular Weight 728.71
Density N/A Boiling Point N/A
Molecular Formula C32H37F9N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Estrogen receptor modulator 10


Estrogen receptor modulator 10 (compound G-5b) is an Estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 can induce apoptosis. Estrogen receptor modulator 10 can block cells at the G1/G0 phase. Estrogen receptor modulator 10 can be used in cancer studies[1].

 Names

Name Estrogen receptor modulator 10

 Estrogen receptor modulator 10 Biological Activity

Description Estrogen receptor modulator 10 (compound G-5b) is an Estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 can induce apoptosis. Estrogen receptor modulator 10 can block cells at the G1/G0 phase. Estrogen receptor modulator 10 can be used in cancer studies[1].
Related Catalog
Target

IC50=6.7 nM, DC50=0.4 nM

References

[1]. Bingsi Wang, et al.A novel scaffold long-acting selective estrogen receptor antagonist and degrader with superior preclinical profile against ER+ breast cancer,European Journal of Medicinal Chemistry,2023.

 Chemical & Physical Properties

Molecular Formula C32H37F9N4O3S
Molecular Weight 728.71
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