2991504-90-4

2991504-90-4 structure

Name: Estrogen receptor modulator 10
Chemical Name: Estrogen receptor modulator 10
CAS Number: 2991504-90-4
Molecular Formula: C₃₂H₃₇F₉N₄O₃S
Molecular Weight: 728.71
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2023-12-26 13:49:47
Modify Date: 2024-02-10 18:53:28
Estrogen receptor modulator 10 (compound G-5b) is an Estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 can induce apoptosis. Estrogen receptor modulator 10 can block cells at the G1/G0 phase. Estrogen receptor modulator 10 can be used in cancer studies[1].

Name	Estrogen receptor modulator 10

Description	Estrogen receptor modulator 10 (compound G-5b) is an Estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). Estrogen receptor modulator 10 can induce apoptosis. Estrogen receptor modulator 10 can block cells at the G1/G0 phase. Estrogen receptor modulator 10 can be used in cancer studies[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase
Target	IC50=6.7 nM, DC50=0.4 nM
References	[1]. Bingsi Wang, et al.A novel scaffold long-acting selective estrogen receptor antagonist and degrader with superior preclinical profile against ER+ breast cancer,European Journal of Medicinal Chemistry,2023.

Molecular Formula	C₃₂H₃₇F₉N₄O₃S
Molecular Weight	728.71