Pim-1 kinase inhibitor 5

Modify Date: 2024-01-16 18:55:30

Pim-1 kinase inhibitor 5 structure	Common Name	Pim-1 kinase inhibitor 5
	CAS Number	2928606-67-9	Molecular Weight	406.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₃Cl₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pim-1 kinase inhibitor 5

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

Name	Pim-1 kinase inhibitor 5

Description	Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
References	[1]. Mansour B, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.

Molecular Formula	C₂₂H₁₃Cl₂N₃O
Molecular Weight	406.26

Pim-1 kinase inhibitor 5

Use of Pim-1 kinase inhibitor 5

Names

Pim-1 kinase inhibitor 5 Biological Activity

Chemical & Physical Properties