WM-586

Modify Date: 2025-08-26 08:54:09

WM-586 Structure
WM-586 structure
 Common Name WM-586
CAS Number 2894832-05-2 Molecular Weight 467.46
Density N/A Boiling Point N/A
Molecular Formula C20H20F3N5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of WM-586


WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1].

 Names

Name WM-586

 WM-586 Biological Activity

Description WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1].
Related Catalog
Target

IC50: 101 nM (WDR5 and MYC interaction)[1]

References

[1]. Ding J, et al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18(1):34-40.  

 Chemical & Physical Properties

Molecular Formula C20H20F3N5O3S
Molecular Weight 467.46
InChIKey BWWWIQSHXJUWBT-ZDUSSCGKSA-N
SMILES CCCCC(Cc1c(F)cc(-c2cccc(S(=O)(=O)F)c2)cc1F)C(=O)Nc1nn[nH]n1
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Chemsrc provides WM-586(CAS#:2894832-05-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of WM-586 are included as well.>> amp version: WM-586

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