LC-MB12
Modify Date: 2024-01-11 14:47:35
LC-MB12 structure
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Common Name | LC-MB12 | ||
|---|---|---|---|---|
| CAS Number | 2828438-38-4 | Molecular Weight | 899.78 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H44Cl2N10O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LC-MB12LC-MB12 is an orally active PROTAC compound targets FGFR2 degradation with a DC50 of 11.8 nM. LC-MB12 contains BGJ398 (a FGFR2 inhibitor), PROTAC linker and CRBN.LC-MB12 inhibits FGFR2 signaling in gastric cancer cells and has anti-tumor activity[1]. |
| Name | LC-MB12 |
|---|
| Description | LC-MB12 is an orally active PROTAC compound targets FGFR2 degradation with a DC50 of 11.8 nM. LC-MB12 contains BGJ398 (a FGFR2 inhibitor), PROTAC linker and CRBN.LC-MB12 inhibits FGFR2 signaling in gastric cancer cells and has anti-tumor activity[1]. |
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| Related Catalog | |
| Target |
FGFR2:11.8 nM (DC50) |
| References |
| Molecular Formula | C43H44Cl2N10O8 |
|---|---|
| Molecular Weight | 899.78 |