PROTAC α-synuclein degrader 5

Modify Date: 2024-04-03 12:50:22

PROTAC α-synuclein degrader 5 Structure
PROTAC α-synuclein degrader 5 structure
Common Name PROTAC α-synuclein degrader 5
CAS Number 2781922-42-5 Molecular Weight 767.78
Density N/A Boiling Point N/A
Molecular Formula C39H41N7O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC α-synuclein degrader 5


PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research[1].

 Names

Name PROTAC α-synuclein degrader 5

 PROTAC α-synuclein degrader 5 Biological Activity

Description PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research[1].
Related Catalog
References

[1]. Yichen Tong, et.al. Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates. Journal of Medicinal Chemistry 2023 66 (12), 7926-7942

 Chemical & Physical Properties

Molecular Formula C39H41N7O10
Molecular Weight 767.78
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