PROTAC BTK Degrader-6

Modify Date: 2024-01-13 18:18:56

PROTAC BTK Degrader-6 structure	Common Name	PROTAC BTK Degrader-6
	CAS Number	2767204-39-5	Molecular Weight	837.92
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₅H₄₇N₁₁O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC BTK Degrader-6

PROTAC BTK Degrader-6 (Compound 15) is a PROTAC BTK degrader (DC50: 3.18 nM. PROTAC BTK Degrader-6 has anti-inflammatory activity, inhibits NF-κB activation, and inhibits the expression of pro-inflammatory cytokines (e.g. IL-1β, IL-6)[1].

Name	PROTAC BTK Degrader-6

Description	PROTAC BTK Degrader-6 (Compound 15) is a PROTAC BTK degrader (DC50: 3.18 nM. PROTAC BTK Degrader-6 has anti-inflammatory activity, inhibits NF-κB activation, and inhibits the expression of pro-inflammatory cytokines (e.g. IL-1β, IL-6)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk Signaling Pathways >> PROTAC >> PROTAC
Target	3.18 nM (BTK)[1]
References	[1]. Huang J, et al. Discovery of Ibrutinib-based BTK PROTACs with in vivo anti-inflammatory efficacy by inhibiting NF-κB activation. Eur J Med Chem. 2023 Jul 18;259:115664.

Molecular Formula	C₄₅H₄₇N₁₁O₆
Molecular Weight	837.92

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PROTAC BTK Degrader-6

Use of PROTAC BTK Degrader-6

Names

PROTAC BTK Degrader-6 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.