KRAS G12C inhibitor 49

Modify Date: 2024-01-13 07:18:46

KRAS G12C inhibitor 49 Structure
KRAS G12C inhibitor 49 structure
Common Name KRAS G12C inhibitor 49
CAS Number 2761380-32-7 Molecular Weight 571.07
Density N/A Boiling Point N/A
Molecular Formula C31H31ClN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12C inhibitor 49


KRAS G12C inhibitor 49 (Compound 3-2M) is an orally active KRAS G12C inhibitor. KRAS G12C inhibitor 49 shows antitumor activity[1].

 Names

Name KRAS G12C inhibitor 49

 KRAS G12C inhibitor 49 Biological Activity

Description KRAS G12C inhibitor 49 (Compound 3-2M) is an orally active KRAS G12C inhibitor. KRAS G12C inhibitor 49 shows antitumor activity[1].
Related Catalog
Target

KRAS(G12C)

In Vitro KRAS G12C inhibitor 49 (Compound 3-2M) shows antiproliferative activity against MIAPaCa-2 and H358 with IC50 values of both 0-50 nM[1].
References

[1]. ZHANG Qiang, et al. Aromatic compound and application thereof in antitumor drug. WO2022028346A1.

 Chemical & Physical Properties

Molecular Formula C31H31ClN6O3
Molecular Weight 571.07