KRAS G12C inhibitor 43

Modify Date: 2024-01-08 19:52:49

KRAS G12C inhibitor 43 Structure
KRAS G12C inhibitor 43 structure
Common Name KRAS G12C inhibitor 43
CAS Number 2648808-69-7 Molecular Weight 577.68
Density N/A Boiling Point N/A
Molecular Formula C33H35N7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12C inhibitor 43


KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].

 Names

Name KRAS G12C inhibitor 43

 KRAS G12C inhibitor 43 Biological Activity

Description KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].
Related Catalog
Target

KRas G12C

References

[1]. Xu Wei, et al. Pyridopyrimidine kras g12c mutant protein inhibitor. WO2021139678A1.

 Chemical & Physical Properties

Molecular Formula C33H35N7O3
Molecular Weight 577.68
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