KRAS G12C inhibitor 43

Modify Date: 2024-01-08 19:52:49

KRAS G12C inhibitor 43 structure	Common Name	KRAS G12C inhibitor 43
	CAS Number	2648808-69-7	Molecular Weight	577.68
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₃₅N₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS G12C inhibitor 43

KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].

Name	KRAS G12C inhibitor 43

Description	KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C
References	[1]. Xu Wei, et al. Pyridopyrimidine kras g12c mutant protein inhibitor. WO2021139678A1.

Molecular Formula	C₃₃H₃₅N₇O₃
Molecular Weight	577.68

KRAS G12C inhibitor 43

Use of KRAS G12C inhibitor 43

Names

KRAS G12C inhibitor 43 Biological Activity

Chemical & Physical Properties