JAK1-IN-11

Modify Date: 2025-09-02 19:06:12

JAK1-IN-11 Structure
JAK1-IN-11 structure
Common Name JAK1-IN-11
CAS Number 2427608-43-1 Molecular Weight 528.67
Density N/A Boiling Point N/A
Molecular Formula C26H36N6O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JAK1-IN-11


JAK1-IN-11 (compound 11) is a potent inhibitor of JAK,with IC50s of 0.02 nM (JAK1),and 0.44 nM (JAK2),respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].

 Names

Name JAK1-IN-11

 JAK1-IN-11 Biological Activity

Description JAK1-IN-11 (compound 11) is a potent inhibitor of JAK,with IC50s of 0.02 nM (JAK1),and 0.44 nM (JAK2),respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].
Related Catalog
Target

IC50: 0.02 nM (JAK1) 和 0.44 nM (JAK2)[1]

References

[1]. Shen W. et al. Amide or sulfonamide substituted hydrazine derivative applied as JAK kinase inhibitor. China, CN110724142 A. 2020-01-24.

 Chemical & Physical Properties

Molecular Formula C26H36N6O4S
Molecular Weight 528.67
InChIKey CMZLROFEPZYUSV-LBISXTPBSA-N
SMILES CC(O)c1nc2cnc3[nH]ccc3c2n1N1CCC(CNS(=O)(=O)CC23CCC(CC2=O)C3(C)C)CC1
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