JAK1-IN-11 structure
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Common Name | JAK1-IN-11 | ||
|---|---|---|---|---|
| CAS Number | 2427608-43-1 | Molecular Weight | 528.67 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H36N6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JAK1-IN-11JAK1-IN-11 (compound 11) is a potent inhibitor of JAK,with IC50s of 0.02 nM (JAK1),and 0.44 nM (JAK2),respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1]. |
| Name | JAK1-IN-11 |
|---|
| Description | JAK1-IN-11 (compound 11) is a potent inhibitor of JAK,with IC50s of 0.02 nM (JAK1),and 0.44 nM (JAK2),respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1]. |
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| Related Catalog | |
| Target |
IC50: 0.02 nM (JAK1) 和 0.44 nM (JAK2)[1] |
| References |
| Molecular Formula | C26H36N6O4S |
|---|---|
| Molecular Weight | 528.67 |
| InChIKey | CMZLROFEPZYUSV-LBISXTPBSA-N |
| SMILES | CC(O)c1nc2cnc3[nH]ccc3c2n1N1CCC(CNS(=O)(=O)CC23CCC(CC2=O)C3(C)C)CC1 |