Benz-AP

Modify Date: 2024-01-29 09:31:39

Benz-AP Structure
Benz-AP structure
Common Name Benz-AP
CAS Number 2416220-53-4 Molecular Weight 299.32
Density N/A Boiling Point N/A
Molecular Formula C20H13NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benz-AP


Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].

 Names

Name Benz-AP

 Benz-AP Biological Activity

Description Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].
Related Catalog
References

[1]. Kailass K, et al. Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence. J Med Chem. 2022 Jun 14.

 Chemical & Physical Properties

Molecular Formula C20H13NO2
Molecular Weight 299.32