2416220-53-4

2416220-53-4 structure

Name: Benz-AP
Chemical Name: Benz-AP
CAS Number: 2416220-53-4
Molecular Formula: C₂₀H₁₃NO₂
Molecular Weight: 299.32
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
Create Date: 2022-08-16 16:10:36
Modify Date: 2024-01-29 09:31:39
Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].

Name	Benz-AP

Description	Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
References	[1]. Kailass K, et al. Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence. J Med Chem. 2022 Jun 14.

Molecular Formula	C₂₀H₁₃NO₂
Molecular Weight	299.32