Sonrotoclax

Modify Date: 2024-01-07 06:20:17

Sonrotoclax Structure
Sonrotoclax structure
Common Name Sonrotoclax
CAS Number 2383086-06-2 Molecular Weight 890.10
Density N/A Boiling Point N/A
Molecular Formula C49H59N7O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sonrotoclax


Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines[1].

 Names

Name Sonrotoclax

 Sonrotoclax Biological Activity

Description Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines[1].
Related Catalog
In Vivo Sonrotoclax (compound 1; 5-50 mg/kg; p.o.; 每日一次, 持续 42 天; 患有急性淋巴细胞白血病 (ALL) 异种移植物的雌性 NCG 小鼠) 具有抗肿瘤活性并抑制肿瘤生长[1]。 Animal Model: Female NCG mice with acute lymphoblastic leukemia (ALL) xenografts[1] Dosage: 5, 15, 50 mg/kg Administration: oral administration; daily, for 42 days Result: Inhibited tumor growth in a dose-dependent manner.
References

[1]. Nan HU, et, al. Methods of cancer treatment using bcl-2 inhibitor. WO2021110102A1.

 Chemical & Physical Properties

Molecular Formula C49H59N7O7S
Molecular Weight 890.10
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