Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

Modify Date: 2024-01-09 11:38:46

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 Structure
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 structure
Common Name Mal-Phe-C4-VC-PAB-DMEA-PNU-159682
CAS Number 2259318-54-0 Molecular Weight 1402.46
Density N/A Boiling Point N/A
Molecular Formula C70H83N9O22 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-Phe-C4-VC-PAB-DMEA-PNU-159682


Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].

 Names

Name Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

 Mal-Phe-C4-VC-PAB-DMEA-PNU-159682 Biological Activity

Description Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
Related Catalog
References

[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

 Chemical & Physical Properties

Molecular Formula C70H83N9O22
Molecular Weight 1402.46