KRAS G12C inhibitor 47

Modify Date: 2024-01-05 18:27:35

KRAS G12C inhibitor 47 structure	Common Name	KRAS G12C inhibitor 47
	CAS Number	2253119-24-1	Molecular Weight	547.02
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₈ClFN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS G12C inhibitor 47

KRAS G12C inhibitor 47 (compound 8-1-1) is a potent KRAS G12C inhibitor with an IC50 of 0.172 µM. KRAS G12C inhibitor 47 shows p-ERK inhibition activities with IC50s of 0.046, 69.8 µM in MIA PaCA-2, A549 cells, respectively. KRAS G12C inhibitor 47 has the potential for the research of pancreatic, colorectal, and lung cancers[1].

Name	KRAS G12C inhibitor 47

Description	KRAS G12C inhibitor 47 (compound 8-1-1) is a potent KRAS G12C inhibitor with an IC50 of 0.172 µM. KRAS G12C inhibitor 47 shows p-ERK inhibition activities with IC50s of 0.046, 69.8 µM in MIA PaCA-2, A549 cells, respectively. KRAS G12C inhibitor 47 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:0.172 μM (IC50)
References	[1]. Brian alan, et al. KRAS g12c inhibitors and methods of using the same. WO2018119183 A2

Molecular Formula	C₃₀H₂₈ClFN₄O₃
Molecular Weight	547.02

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

KRAS G12C inhibitor 47

Use of KRAS G12C inhibitor 47

Names

KRAS G12C inhibitor 47 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.