URAT1 inhibitor 6

Modify Date: 2024-04-09 09:53:35

URAT1 inhibitor 6 Structure
URAT1 inhibitor 6 structure
Common Name URAT1 inhibitor 6
CAS Number 2244807-49-4 Molecular Weight 356.19
Density N/A Boiling Point N/A
Molecular Formula C9H7BrN3NaO2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of URAT1 inhibitor 6


URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6 is 200- and 8-fold more potent than parent Lesinurad (HY-15258) and Benzbromarone (HY-B1135). URAT1 inhibitor 6 can be used for research of inflammation[1].

 Names

Name URAT1 inhibitor 6

 URAT1 inhibitor 6 Biological Activity

Description URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6 is 200- and 8-fold more potent than parent Lesinurad (HY-15258) and Benzbromarone (HY-B1135). URAT1 inhibitor 6 can be used for research of inflammation[1].
Related Catalog
References

[1]. Cai W, et al. Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor. Molecules. 2018 Jan 27;23(2):252.  

 Chemical & Physical Properties

Molecular Formula C9H7BrN3NaO2S2
Molecular Weight 356.19
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