Anticancer agent 147

Modify Date: 2024-09-15 18:02:43

Anticancer agent 147 structure	Common Name	Anticancer agent 147
	CAS Number	2241283-11-2	Molecular Weight	578.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₄₀BrN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anticancer agent 147

Anticancer agent 147 (compound 6j) is a derivative of sophoridine (HY-N1373) and is a ferroptosis inducer. Anticancer agent 147 can promote the accumulation of intracellular Fe2+, reactive oxygen species (ROS) and MDA, increase ER stress, and upregulate the expression of the activating transcription factor ATF3. Anticancer agent 147 has good anti-liver cancer effects in vitro and in vivo[1].

Name	Anticancer agent 147

Description	Anticancer agent 147 (compound 6j) is a derivative of sophoridine (HY-N1373) and is a ferroptosis inducer. Anticancer agent 147 can promote the accumulation of intracellular Fe2+, reactive oxygen species (ROS) and MDA, increase ER stress, and upregulate the expression of the activating transcription factor ATF3. Anticancer agent 147 has good anti-liver cancer effects in vitro and in vivo[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
References	[1]. Tian K, et al. Sophoridine derivative 6j inhibits liver cancer cell proliferation via ATF3 mediated ferroptosis. Cell Death Discov. 2023 Aug 14;9(1):296..

Molecular Formula	C₃₂H₄₀BrN₃O₂
Molecular Weight	578.58

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Anticancer agent 147

Use of Anticancer agent 147

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Anticancer agent 147 Biological Activity

Chemical & Physical Properties

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