IDO1-IN-22

Modify Date: 2024-04-03 20:55:50

IDO1-IN-22 structure	Common Name	IDO1-IN-22
	CAS Number	2126853-16-3	Molecular Weight	387.16
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₂BrFN₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDO1-IN-22

IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile[1].

Name	IDO1-IN-22

Description	IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Inflammation/Immunology
References	[1]. Ye K, et al. Design, synthesis, biological evaluation of urea substituted 1,2,5-oxadiazole-3-carboximidamides as novel indoleamine 2,3-dioxygenase-1 (IDO1) inhibitors. Eur J Med Chem. 2023 Mar 15;250:115217.

Molecular Formula	C₁₂H₁₂BrFN₆O₃
Molecular Weight	387.16

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

IDO1-IN-22

Use of IDO1-IN-22

Names

IDO1-IN-22 Biological Activity

Chemical & Physical Properties