(R)-Azasetron besylate

Modify Date: 2025-08-28 17:42:17

(R)-Azasetron besylate structure	Common Name	(R)-Azasetron besylate
	CAS Number	2025360-91-0	Molecular Weight	507.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₆ClN₃O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-Azasetron besylate

(R)-Azasetron besylate (SENS-401) is an orally active calcineurin inhibitor. (R)-Azasetron besylate reduces Cisplatin (HY-17394)-induced hearing loss and cochlear damage[1][2].

Name	(R)-Azasetron besylate

Description	(R)-Azasetron besylate (SENS-401) is an orally active calcineurin inhibitor. (R)-Azasetron besylate reduces Cisplatin (HY-17394)-induced hearing loss and cochlear damage[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
References	[1]. Petremann M, et al. SENS-401 Effectively Reduces Severe Acoustic Trauma-Induced Hearing Loss in Male Rats With Twice Daily Administration Delayed up to 96 hours. Otol Neurotol. 2019 Feb;40(2):254-263. [2]. Petremann M, et al. Oral Administration of Clinical Stage Drug Candidate SENS-401 Effectively Reduces Cisplatin-induced Hearing Loss in Rats. Otol Neurotol. 2017 Oct;38(9):1355-1361.

Description

(R)-Azasetron besylate (SENS-401) is an orally active calcineurin inhibitor. (R)-Azasetron besylate reduces Cisplatin (HY-17394)-induced hearing loss and cochlear damage[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

References

[1]. Petremann M, et al. SENS-401 Effectively Reduces Severe Acoustic Trauma-Induced Hearing Loss in Male Rats With Twice Daily Administration Delayed up to 96 hours. Otol Neurotol. 2019 Feb;40(2):254-263.

[2]. Petremann M, et al. Oral Administration of Clinical Stage Drug Candidate SENS-401 Effectively Reduces Cisplatin-induced Hearing Loss in Rats. Otol Neurotol. 2017 Oct;38(9):1355-1361.

Molecular Formula	C₂₃H₂₆ClN₃O₆S
Molecular Weight	507.99
InChIKey	GFVBDLIBPSGFDL-ZOWNYOTGSA-N
SMILES	CN1C(=O)COc2c(C(=O)NC3CN4CCC3CC4)cc(Cl)cc21.O=S(=O)(O)c1ccccc1

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(R)-Azasetron besylate

Use of (R)-Azasetron besylate

Names

(R)-Azasetron besylate Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.