Zamaporvint

Modify Date: 2024-04-03 12:19:41

Zamaporvint Structure
Zamaporvint structure
Common Name Zamaporvint
CAS Number 1900754-56-4 Molecular Weight 439.39
Density N/A Boiling Point N/A
Molecular Formula C21H16F3N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zamaporvint


Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research[1].

 Names

Name Zamaporvint

 Zamaporvint Biological Activity

Description Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research[1].
Related Catalog
References

[1]. Phillips C, The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand-dependent Cancer Models. Cancer Res Commun. 2022 Sep 2;2(9):914-928.  

 Chemical & Physical Properties

Molecular Formula C21H16F3N7O
Molecular Weight 439.39
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