NF-κB-IN-3

Modify Date: 2025-08-26 08:44:06

NF-κB-IN-3 Structure
NF-κB-IN-3 structure
Common Name NF-κB-IN-3
CAS Number 1873311-82-0 Molecular Weight 458.86
Density N/A Boiling Point N/A
Molecular Formula C24H18ClF3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NF-κB-IN-3


NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].

 Names

Name NF-κB-IN-3

 NF-κB-IN-3 Biological Activity

Description NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].
Related Catalog
Target

NF-κB:0.70 μM (IC50)

References

[1]. Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.

 Chemical & Physical Properties

Molecular Formula C24H18ClF3N2O2
Molecular Weight 458.86
InChIKey AQAHZVKARZMSBW-UHFFFAOYSA-N
SMILES O=C(Nc1ccccc1C(F)(F)F)C1CCc2ccccc2N1C(=O)c1cccc(Cl)c1
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