Cyprodinil-13C6

Modify Date: 2024-01-09 09:04:22

Cyprodinil-13C6 structure	Common Name	Cyprodinil-13C6
	CAS Number	1773496-63-1	Molecular Weight	231.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₁₃C₆H₁₅N₃	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of Cyprodinil-13C6

Cyprodinil-13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).

Name	Cyprodinil-13C6

Description	Cyprodinil-13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
Related Catalog	Research Areas >> Endocrinology Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Others >> Androgen Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [2]. Masner, P., et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci. 42(3),163-166 (1994). [3]. Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.

Molecular Formula	C₈₁₃C₆H₁₅N₃
Molecular Weight	231.24

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H315-H317-H319-H410
Precautionary Statements	P273-P280-P333 + P313-P337 + P313-P391
RIDADR	UN 3077 9 / PGIII

Cyprodinil-13C6

Use of Cyprodinil-13C6

Names

Cyprodinil-13C6 Biological Activity

Chemical & Physical Properties

Safety Information