Sulfo-ara-F-NMN
Modify Date: 2024-01-31 19:02:56
Sulfo-ara-F-NMN structure
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Common Name | Sulfo-ara-F-NMN | ||
|---|---|---|---|---|
| CAS Number | 1639300-84-7 | Molecular Weight | 353.28 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H15FN2O6PS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Sulfo-ara-F-NMNSulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production[1]. |
| Name | Sulfo-ara-F-NMN |
|---|
| Description | Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production[1]. |
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| In Vitro | Sterile alpha and Toll/interleukin-1 receptor motif-containing 1 (SARM1) is an adaptor protein in the Toll-like receptor pathway. Sulfo-ara-F-NMN activates SARM1 to produce cyclic ADP-ribose and induces non-apoptotic cell death[1]. |
| References |
| Molecular Formula | C11H15FN2O6PS |
|---|---|
| Molecular Weight | 353.28 |