GAD65 (524-543)

Modify Date: 2025-08-25 17:05:48

GAD65 (524-543) Structure
GAD65 (524-543) structure
Common Name GAD65 (524-543)
CAS Number 152468-44-5 Molecular Weight 2238.67
Density N/A Boiling Point N/A
Molecular Formula C97H168N28O28S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GAD65 (524-543)


GAD65 (524-543) is a biological active peptide. (This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.)

 Names

Name GAD65 (524-543)

 GAD65 (524-543) Biological Activity

Description GAD65 (524-543) is a biological active peptide. (This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.)
Related Catalog

 Chemical & Physical Properties

Molecular Formula C97H168N28O28S2
Molecular Weight 2238.67
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