Isophysalin A
Modify Date: 2024-02-12 17:54:18
Isophysalin A structure
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Common Name | Isophysalin A | ||
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| CAS Number | 1363398-67-7 | Molecular Weight | 526.53 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 846.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C28H30O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 286.6±27.8 °C | |
Use of Isophysalin AIsophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity[1]. |
| Name | (1S,2S,3S,5R,6S,7R,14R,15S,18S,21S)-5,7,18-Trihydroxy-1,14,21-trimethyl-25-methylene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone |
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| Synonym | More Synonyms |
| Description | Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 846.6±65.0 °C at 760 mmHg |
| Molecular Formula | C28H30O10 |
| Molecular Weight | 526.53 |
| Flash Point | 286.6±27.8 °C |
| Exact Mass | 526.183899 |
| LogP | 2.60 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.669 |
| Hazard Codes | Xi |
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| (1S,2S,3S,5R,6S,7R,14R,15S,18S,21S)-5,7,18-Trihydroxy-1,14,21-trimethyl-25-methylene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone |
| 1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,10H)-tetrone, 2,3,6,6a,8a,9,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-, (1S,2S,6aS,8aS,10aS,10bR,16R,16aS,17R,18aS)- |