Pegylated synthetic human c-peptide

Modify Date: 2024-01-03 14:08:54

Pegylated synthetic human c-peptide structure	Common Name	Pegylated synthetic human c-peptide
	CAS Number	1350661-05-0	Molecular Weight	3018.52
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂₉H₂₁₁N₃₅O₄₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pegylated synthetic human c-peptide

Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].

Name	Pegylated synthetic human c-peptide

Description	Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Pegylated synthetic human c-peptide (CBX129801) (s.c., 0.4, 1.33 or 4.0 mg/kg/wk, 39 weeks) 可以导致给药后注射部位组织中空泡化巨噬细胞的细胞质浸润和引流腋窝淋巴结，而不会导致全身巨噬细胞空泡化[1]。
References	[1]. Dennis Naas, et al. A 9-Month Toxicity and Toxicokinetic Assessment of Subcutaneous Pegylated Human C-peptide (CBX129801) in Cynomolgus Monkeys. Int J Toxicol. 2015 Jul-Aug;34(4):318-24.

Molecular Formula	C₁₂₉H₂₁₁N₃₅O₄₈
Molecular Weight	3018.52

Pegylated synthetic human c-peptide

Use of Pegylated synthetic human c-peptide

Names

Pegylated synthetic human c-peptide Biological Activity

Chemical & Physical Properties