Hyzetimibe

Modify Date: 2024-01-21 15:45:43

Hyzetimibe Structure
Hyzetimibe structure
Common Name Hyzetimibe
CAS Number 1266548-74-6 Molecular Weight 421.44
Density N/A Boiling Point N/A
Molecular Formula C25H21F2NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hyzetimibe


Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].

 Names

Name Hyzetimibe

 Hyzetimibe Biological Activity

Description Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].
Related Catalog
References

[1]. Ruan Z, et al. Pharmacokinetics, pharmacodynamics, safety, and tolerability of hyzetimibe (HS-25) in healthy Chinese subjects. J Clin Pharmacol. 2014 Oct;54(10):1144-52.  

 Chemical & Physical Properties

Molecular Formula C25H21F2NO3
Molecular Weight 421.44
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