Microtubule inhibitor 3

Modify Date: 2024-01-07 14:40:55

Microtubule inhibitor 3 structure	Common Name	Microtubule inhibitor 3
	CAS Number	1236141-96-0	Molecular Weight	458.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₃FN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Microtubule inhibitor 3

Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.

Name	Microtubule inhibitor 3

Description	Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ding Z,et al. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer. Bioorg Med Chem. 2020 May 15;28(10):115435.

Molecular Formula	C₂₆H₂₃FN₄O₃
Molecular Weight	458.48