BOC-L-phenylalanine-d8

Modify Date: 2024-01-09 18:14:55

BOC-L-phenylalanine-d8 Structure
BOC-L-phenylalanine-d8 structure
Common Name BOC-L-phenylalanine-d8
CAS Number 106881-07-6 Molecular Weight 273.35
Density N/A Boiling Point N/A
Molecular Formula C14H11D8NO4 Melting Point 85-87ºC(lit.)
MSDS Chinese USA Flash Point N/A

 Use of BOC-L-phenylalanine-d8


BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine[1].

 Names

Name (2S)-2,3,3-trideuterio-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2,3,4,5,6-pentadeuteriophenyl)propanoic acid
Synonym More Synonyms

 BOC-L-phenylalanine-d8 Biological Activity

Description BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Melting Point 85-87ºC(lit.)
Molecular Formula C14H11D8NO4
Molecular Weight 273.35
Exact Mass 273.18200
PSA 75.63000
LogP 2.59790

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

Boc-Phe-OH-phenyl-d5-2,3,3-d3
L-Phenyl-d5-alanine-2,3,3-d3,N-t-Boc derivative
MFCD01075441