Nebadensin

Modify Date: 2025-08-19 20:20:03

Nebadensin structure	Common Name	Nebadensin
	CAS Number	152743-19-6	Molecular Weight	344.315
	Density	1.4±0.1 g/cm3	Boiling Point	615.0±55.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₆O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	227.0±25.0 °C

Use of Nebadensin

Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].

Name	lysionotin
Synonym	More Synonyms

Description	Lysionotin is a flavonoid isolated from few flower lysionotus herbs. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: α-Toxin[1]
References	[1]. Teng Z, et al.Lysionotin attenuates Staphylococcus aureus pathogenicity by inhibiting α-toxin expression.Appl Microbiol Biotechnol. 2017 Sep;101(17):6697-6703.

Density	1.4±0.1 g/cm3
Boiling Point	615.0±55.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₆O₇
Molecular Weight	344.315
Flash Point	227.0±25.0 °C
Exact Mass	344.089600
PSA	98.36000
LogP	1.79
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.627

Name: Induction of quinone reductase
Source: ChEMBL
Target: NAD(P)H dehydrogenase [quinone] 1
External Id: CHEMBL1004305

Name: Inhibition of rat lens aldose reductase
Source: ChEMBL
Target: Aldo-keto reductase family 1 member B1
External Id: CHEMBL981183

Name: In vitro cytotoxic potency against NCI-60 human tumor cell line
Source: ChEMBL
Target: Panel NCI-60 (60 carcinoma cell lines)
External Id: CHEMBL749609

Name: Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells pre-incubated for ...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3388890

Name: Kinase Assay from Article 10.1002/cbic.201000487: "Biological evaluation and structur...
Source: BindingDB
Target: N/A
External Id: BindingDB_5042_1

Name: Inhibition of bovine thymocytes protein tyrosine kinase assessed as angiotensin 1 pho...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1015773

Name: Cytotoxicity against mouse RAW264.7 cells at 0.01 to 100 uM after 24 hrs by MTT assay
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3389454

Name: Toxicity against brine shrimp
Source: ChEMBL
Target: Artemia
External Id: CHEMBL1000955

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Nebadensin

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