Copper Tripeptide-1 (GHK-Cu)

Published date: 2026-05-22 10:54:00

Copper Tripeptide-1 (GHK-Cu) Structure
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Name Copper Peptide CAS# 49557-75-7
Price $83.85/100mg Purity 98.25%
Stocking
Period
3 Day Stock Inquiry
Product Webpage: http://www.zhaokebio.com
 Detail Product Information
GHK-Cu (Copper Tripeptide-1), also known as Blue Copper Peptide, is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK). First isolated from human plasma by Loren Pickart in 1973, GHK-Cu has emerged as one of the most extensively researched bioactive peptides in the fields of dermatology, cosmetic science, and regenerative medicine. It is naturally present in human plasma, saliva, and urine, with concentrations declining significantly from age 20 to 60, a pattern that directly correlates with reduced tissue repair capacity and visible signs of aging.
The GHK tripeptide exhibits high affinity for copper ions, forming a stable 1:1 coordination complex where the copper(II) ion binds to histidine's imidazole nitrogen and adjacent peptide backbone nitrogens. This precise coordination geometry is essential for biological activity. GHK-Cu functions as a potent signaling molecule that stimulates fibroblast proliferation, enhances collagen and elastin synthesis, promotes glycosaminoglycan production (including hyaluronic acid), and supports tissue remodeling. It also exhibits antioxidant, anti-inflammatory, and wound-healing properties, making it a true multifunctional active ingredient.
Research has demonstrated that GHK-Cu can upregulate and downregulate a large number of human genes, including those critical for tissue repair, anti-inflammatory responses, and antioxidant defense. Over 300 peer-reviewed studies have confirmed its ability to stimulate collagen synthesis, enhance wound healing, reduce oxidative stress, and modulate inflammatory cytokines. As a specialized API sourcing partner, Shenzhen Zhaoke Biotechnology Co., Ltd. provides high-purity GHK-Cu (CAS No.: 49557-75-7) with comprehensive analytical documentation for global cosmetic manufacturers, pharmaceutical companies, and research institutions.
Key Selling Points:
50+ Years Research: Discovered in 1973; 300+ peer-reviewed publications; Most extensively studied cosmetic peptide with robust clinical evidence
Multi-Functional: Collagen/elastin synthesis + antioxidant + anti-inflammatory + wound healing; One ingredient addresses multiple skin concerns simultaneously
Gene Regulation: Up/downregulates hundreds of human genes related to tissue repair; Works at the genetic level for comprehensive skin rejuvenation
Stable Cu Complex: 1:1 Cu²⁺ chelation with verified 11.9-12.2% copper content; Precise coordination ensures consistent bioactivity batch-to-batch
Water-Soluble: Very soluble in water; compatible with aqueous cosmetic formulations; Easy integration into serums, creams, and toners
One-Stop Procurement: Consolidated sourcing for cosmetic peptides and active ingredients; Reduces supplier management complexity and cost

Supplier/Manufacture

Shenzhen Zhaoke Biotechnology Co., Ltd.

Chemsrc Level: Unverified
Tel: 0086-19842673490
Address: Room A207-208, Building A, No.3 Branch Park, Leibo Zhongcheng Life Science Park, Pingshan District, Shenzhen, Guangdong, China, 518118
Area: China
Contact: Jade Cheung
Contact Phone #: 19842673490
Email: jade.cheung@zhaokebio.com
Website: http://www.zhaokebio.com
Major Market: North America, Western Europe, Midde East, South Asia
Annual Trade Volume: 10,000,000
Foreign Trade % of Sales: 100%
Major partners:
Shenzhen Zhaoke Biotechnology Co., Ltd. operates as a specialized global procurement and supply chain solutions provider focused exclusively on high-quality peptide APIs. Rather than manufacturing, our core competency lies in strategically sourcing, rigorously vetting, and reliably delivering premium peptide products from qualified suppliers across the global pharmaceutical landscape.
We serve as the critical link between world-class peptide producers and pharmaceutical R&D enters, research institutions, and manufacturing enterprises across North America, Europe, Asia Pacific, and emerging markets. Our mission is to eliminate procurement complexity, mitigate supply risk, and ensure uncompromising quality at every stage of the sourcing journey.
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Price: ¥108/250mg
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