4H-1-Benzopyran-4-one,6-chloro-2-phenyl

Modify Date: 2026-07-01 12:24:25

4H-1-Benzopyran-4-one,6-chloro-2-phenyl Structure
4H-1-Benzopyran-4-one,6-chloro-2-phenyl structure
Common Name 4H-1-Benzopyran-4-one,6-chloro-2-phenyl
CAS Number 10420-73-2 Molecular Weight 256.68400
Density 1.342g/cm3 Boiling Point 408.8ºC at 760mmHg
Molecular Formula C15H9ClO2 Melting Point 183-185ºC(lit.)
MSDS N/A Flash Point 173.1ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 6-chloro-2-phenylchromen-4-one
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.342g/cm3
Boiling Point 408.8ºC at 760mmHg
Melting Point 183-185ºC(lit.)
Molecular Formula C15H9ClO2
Molecular Weight 256.68400
Flash Point 173.1ºC
Exact Mass 256.02900
PSA 30.21000
LogP 4.11340
Vapour Pressure 6.82E-07mmHg at 25°C
Index of Refraction 1.642
InChIKey IFNDLWHUYFSXBK-UHFFFAOYSA-N
SMILES O=c1cc(-c2ccccc2)oc2ccc(Cl)cc12

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 6-Chloroflavone Material Safety Data Sheet
Synonym: None Known
CAS: 10420-73-2
Section 1 - Chemical Product MSDS Name:6-Chloroflavone Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10420-73-2 6-Chloroflavone 98 unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 10420-73-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 183 - 185 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density:
Molecular Formula: C15H9ClO2
Molecular Weight: 256.69

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 10420-73-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
6-Chloroflavone - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 10420-73-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 10420-73-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 10420-73-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
HS Code 2914700090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 4H-1-Benzopyran-4-one,6-chloro-2-phenylBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

6-Chloroflavone
6-chloro-2-phenyl-chromen-4-one
6-Chloro-2-phenyl-4H-chromen-4-one
6-CHLORFLAVONE
6-chloro-2-phenyl-4H-1-benzopyran-4-one
6-chloroflavanone

 4H-1-Benzopyran-4-one,6-chloro-2-phenyl | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What English synonyms does 6-chloro-2-phenylchromen-4-one have?
A: English synonyms of 6-chloro-2-phenylchromen-4-one: 6-Chloroflavone, 6-chloro-2-phenyl-chromen-4-one, 6-Chloro-2-phenyl-4H-chromen-4-one, 6-CHLORFLAVONE, 6-chloro-2-phenyl-4H-1-benzopyran-4-one, 6-chloroflavanone.
Q: What is the melting point of 6-chloro-2-phenylchromen-4-one?
A: Melting point of 6-chloro-2-phenylchromen-4-one is 183-185ºC(lit.).
Q: What is the molecular formula of 6-chloro-2-phenylchromen-4-one?
A: Molecular formula of 6-chloro-2-phenylchromen-4-one is C15H9ClO2.
Q: What is the LogP of 6-chloro-2-phenylchromen-4-one?
A: LogP of 6-chloro-2-phenylchromen-4-one is 4.11340.
Q: What is the SMILES notation of 6-chloro-2-phenylchromen-4-one?
A: SMILES notation of 6-chloro-2-phenylchromen-4-one is O=c1cc(-c2ccccc2)oc2ccc(Cl)cc12.
Q: What is the InChIKey of 6-chloro-2-phenylchromen-4-one?
A: InChIKey of 6-chloro-2-phenylchromen-4-one is IFNDLWHUYFSXBK-UHFFFAOYSA-N.
Q: What is the molecular weight of 6-chloro-2-phenylchromen-4-one?
A: Molecular weight of 6-chloro-2-phenylchromen-4-one is 256.68400.
Q: What is the CAS number of 6-chloro-2-phenylchromen-4-one?
A: CAS number of 6-chloro-2-phenylchromen-4-one is 10420-73-2.
Q: What is the polar surface area (PSA) of 6-chloro-2-phenylchromen-4-one?
A: Polar surface area (PSA) of 6-chloro-2-phenylchromen-4-one is 30.21000.
Q: What is the boiling point of 6-chloro-2-phenylchromen-4-one?
A: Boiling point of 6-chloro-2-phenylchromen-4-one is 408.8ºC at 760mmHg.

 4H-1-Benzopyran-4-one,6-chloro-2-phenylfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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