4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde

Modify Date: 2026-07-01 13:08:49

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde Structure
4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde structure
Common Name 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde
CAS Number 141103-93-7 Molecular Weight 177.20000
Density 1.181g/cm3 Boiling Point 336.5ºC at 760mmHg
Molecular Formula C10H11NO2 Melting Point 53ºC
MSDS USA Flash Point 157.3ºC

Summary: 4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde, Chinese name: 4-甲基-3,4-二氢-2H-1,4-苯并噁嗪-7-甲醛, CAS number: 141103-93-7, molecular formula: C10H11NO2. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.181g/cm3
Boiling Point 336.5ºC at 760mmHg
Melting Point 53ºC
Molecular Formula C10H11NO2
Molecular Weight 177.20000
Flash Point 157.3ºC
Exact Mass 177.07900
PSA 29.54000
LogP 1.39270
Vapour Pressure 0.000112mmHg at 25°C
Index of Refraction 1.587
InChIKey WJHBKMPLXRGBGM-UHFFFAOYSA-N
SMILES CN1CCOc2cc(C=O)ccc21

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 4-Methyl-3 4-dihydro-2h-1 4-benzoxazine-7-carbaldehyde 97% Material Safety Data Sheet
Synonym:
CAS: 141103-93-7
Section 1 - Chemical Product MSDS Name:4-Methyl-3 4-dihydro-2h-1 4-benzoxazine-7-carbaldehyde 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
141103-93-7 4-Methyl-3,4-dihydro-2H-1,4-benzoxazin 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 141103-93-7: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: pale yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 53 - 55 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H11NO2
Molecular Weight: 177.2

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 141103-93-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-Methyl-3,4-dihydro-2H-1,4-benzoxazine-7-carbaldehyde - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 141103-93-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 141103-93-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 141103-93-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
Safety Phrases S24/25
HS Code 2934999090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~99%

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde Structure

4-Methyl-3,4-di...

CAS#:141103-93-7

Learn More
Literature: MERCK SHARP and DOHME CORP.; KOZLOWSKI, Joseph A.; ROSENBLUM, Stuart B.; COBURN, Craig A.; SHANKAR, Bandarpalle, B.; ANILKUMAR, G., Nair; CHEN, Lei; DWYER, Michael, P.; JIANG, Yueheng; KEERTIKAR, Kartik, M.; LAVEY, Brian, J.; SELYUTIN, Oleg, B.; TONG, Ling; WONG, Michael; YANG, De-Yi; YU, Wensheng; ZHOU, Guowei; WU, Hao; HU, Bin; ZHONG, Bin; SUN, Fei; JI, Tao; SHEN, Changmao; RIZVI, Razia; ZENG, Qingbei Patent: WO2012/41014 A1, 2012 ; Location in patent: Page/Page column 236-237 ;

~76%

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde Structure

4-Methyl-3,4-di...

CAS#:141103-93-7

Learn More
Literature: Kotha, Sambasivarao; Bindra, Vandana; Kuki, Atsuo Heterocycles, 1994 , vol. 38, # 1 p. 5 - 8

~%

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde Structure

4-Methyl-3,4-di...

CAS#:141103-93-7

Learn More
Literature: Kotha, Sambasivarao; Kuki, Atsuo Journal of the Chemical Society, Chemical Communications, 1992 , # 5 p. 404 - 406

~%

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbaldehyde Structure

4-Methyl-3,4-di...

CAS#:141103-93-7

Learn More
Literature: Kotha, Sambasivarao; Kuki, Atsuo Journal of the Chemical Society, Chemical Communications, 1992 , # 5 p. 404 - 406

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of Leishmania major PTR1 at 500 uM
Source: ChEMBL
Target: Pteridine reductase 1
External Id: CHEMBL1655379
Total 1, Current Page 1 of 1
1

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carbaldehyde
2H-1,4-Benzoxazine-7-carboxaldehyde,3,4-dihydro-4-methyl

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: Polar surface area (PSA) of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is 29.54000.
Q: What is the boiling point of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: Boiling point of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is 336.5ºC at 760mmHg.
Q: What are the upstream materials of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: Related upstream materials(CAS) of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde: 68-12-2;154264-95-6;77901-22-5;273-53-0;611-24-5.
Q: What is the CAS number of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: CAS number of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is 141103-93-7.
Q: What is the English name of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: The English name of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde.
Q: What is the LogP of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: LogP of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is 1.39270.
Q: What is the molecular formula of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: Molecular formula of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is C10H11NO2.
Q: What is the InChIKey of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: InChIKey of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is WJHBKMPLXRGBGM-UHFFFAOYSA-N.
Q: What is the SMILES notation of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: SMILES notation of 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde is CN1CCOc2cc(C=O)ccc21.
Q: What is the safety information for 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde?
A: Safety information for 4-methyl-2,3-dihydro-1,4-benzoxazine-7-carbaldehyde: S24/25.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.