N-(3-Oxohexanoyl)homoserine lactone

Modify Date: 2026-07-01 17:20:44

N-(3-Oxohexanoyl)homoserine lactone Structure
N-(3-Oxohexanoyl)homoserine lactone structure
Common Name N-(3-Oxohexanoyl)homoserine lactone
CAS Number 143537-62-6 Molecular Weight 213.230
Density 1.2±0.1 g/cm3 Boiling Point 482.9±45.0 °C at 760 mmHg
Molecular Formula C10H15NO4 Melting Point N/A
MSDS USA Flash Point 245.9±28.7 °C

 Use of N-(3-Oxohexanoyl)homoserine lactone


N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing[1].

 Names

Name N-(.β.-ketocaproyl)-L-Homoserine lactone
Synonym More Synonyms

 N-(3-Oxohexanoyl)homoserine lactone Biological Activity

Description N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing[1].
Related Catalog
References

[1]. Welch M, et al. N-acyl homoserine lactone binding to the CarR receptor determines quorum-sensing specificity in Erwinia. EMBO J. 2000 Feb 15;19(4):631-41.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 482.9±45.0 °C at 760 mmHg
Molecular Formula C10H15NO4
Molecular Weight 213.230
Flash Point 245.9±28.7 °C
Exact Mass 213.100113
PSA 72.47000
LogP -1.17
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.486
InChIKey YRYOXRMDHALAFL-QMMMGPOBSA-N
SMILES CCCC(=O)CC(=O)NC1CCOC1=O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles2

More Articles
Cell adhesion, ammonia removal and granulation of autotrophic nitrifying sludge facilitated by N-acyl-homoserine lactones.

Bioresour. Technol. 196 , 550-8, (2015)

In this study, six N-acyl-homoserine lactone (AHL) molecules (C6-HSL, C8-HSL, C10-HSL, 3-oxo-C6-HSL, 3-oxo-C8-HSL and 3-oxo-C10-HSL) were each dosed into a bioreactor and seeded using autotrophic nitr...

Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators.

Bioorg. Med. Chem. Lett. 18 , 5978-81, (2008)

A focused library of N-aryl l-homoserine lactones was designed around known lactone leads and evaluated for antagonistic and agonistic activity against quorum-sensing receptors in Agrobacterium tumefa...

 N-(3-Oxohexanoyl)homoserine lactoneBioassay

View more

Name: Activation of LasR in Escherichia coli JLD271 harboring pSC11/pJN105L using CPRG as s...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4404077
Name: Agonist activity at Vibrio fischeri ES114 LuxR receptor by luciferase reporter gene a...
Source: ChEMBL
Target: Transcriptional activator protein LuxR
External Id: CHEMBL1019483
Name: Agonist activity at Agrobacterium tumefaciens WCF47 TraR receptor by beta-galctosidas...
Source: ChEMBL
Target: Transcriptional activator protein TraR
External Id: CHEMBL1016860
Name: Agonist activity at Escherichia coli DH5alpha LasR receptor by beta-galctosidase repo...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1019482
Name: Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated...
Source: ChEMBL
Target: Transcriptional activator protein LasR
External Id: CHEMBL4404074
Name: Induction of acylated homoserine lactone system-mediated traI-lacZ reporter gene expr...
Source: ChEMBL
Target: Agrobacterium tumefaciens
External Id: CHEMBL940526
Name: Inhibition of LasR in Escherichia coli JLD271 harboring pSC11/pJN105L using CPRG as s...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4404076
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 Synonyms

3-Oxo-N-(2-oxotetrahydrofuran-3-yl)hexanamide
N-(3-Oxohexanoyl)homoserine lactone
N-(3-Oxohexanoyl)-3-aminodihydro-2(3H)-furanone
3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)hexanamide
3-Oxo-N-(2-oxotetrahydro-3-furanyl)hexanamide
N-(β-ketocaproyl)-DL-homoserine lactone
N-(BETA-KETOCAPROYL)-DL-HOMOSERINE LACTONE
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