2-bromo-1-(4-chloro-3-nitrophenyl)ethanone

Modify Date: 2026-07-01 10:48:34

2-bromo-1-(4-chloro-3-nitrophenyl)ethanone Structure
2-bromo-1-(4-chloro-3-nitrophenyl)ethanone structure
Common Name 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone
CAS Number 22019-49-4 Molecular Weight 278.48700
Density 1.763g/cm3 Boiling Point 336.1ºC at 760mmHg
Molecular Formula C8H5BrClNO3 Melting Point 86-89ºC
MSDS N/A Flash Point 157.1ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.763g/cm3
Boiling Point 336.1ºC at 760mmHg
Melting Point 86-89ºC
Molecular Formula C8H5BrClNO3
Molecular Weight 278.48700
Flash Point 157.1ºC
Exact Mass 276.91400
PSA 62.89000
LogP 3.34900
Vapour Pressure 0.000115mmHg at 25°C
Index of Refraction 1.619
InChIKey FXNQTMRPLLNPQY-UHFFFAOYSA-N
SMILES O=C(CBr)c1ccc(Cl)c([N+](=O)[O-])c1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one tech Material Safety Data Sheet
Synonym: 4-Chloro-3-nitrophenacylbromid
CAS: 22019-49-4
Section 1 - Chemical Product MSDS Name:2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one tech Material Safety Data Sheet
Synonym:4-Chloro-3-nitrophenacylbromid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
22019-49-4 2-Bromo-1-(4-chloro-3-nitrophenyl)etha unlisted
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area. Store under an inert atmosphere.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 22019-49-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 86 - 89 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H5BrClNO3
Molecular Weight: 278

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, bases.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide, bromine.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 22019-49-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3261
Packing Group: III
IMO
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3261
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3261
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 22019-49-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 22019-49-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 22019-49-4 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes C:Corrosive
Risk Phrases 36/37/38
Safety Phrases 22-24/25
HS Code 2914700090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~60%

2-bromo-1-(4-chloro-3-nitrophenyl)ethanone Structure

2-bromo-1-(4-ch...

CAS#:22019-49-4

Learn More
Literature: Shionogi and Co., Ltd. Patent: WO2005/121132 A1, 2005 ; Location in patent: Page/Page column 234-235 ;

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  1

DownStream  1

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-chloro-3-nitrophenacyl bromide
bromo-4'-chloro-3'-nitro-acetophenone
2-Bromo-4'-chloro-3'-nitroacetophenone
2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one
2-bromo-1-(4-chloro-3-nitro-phenyl)ethanone

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular formula of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: Molecular formula of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is C8H5BrClNO3.
Q: What is the English name of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: The English name of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone.
Q: What English synonyms does 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone have?
A: English synonyms of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone: 4-chloro-3-nitrophenacyl bromide, bromo-4'-chloro-3'-nitro-acetophenone, 2-Bromo-4'-chloro-3'-nitroacetophenone, 2-Bromo-1-(4-chloro-3-nitrophenyl)ethan-1-one, 2-bromo-1-(4-chloro-3-nitro-phenyl)ethanone.
Q: What is the CAS number of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: CAS number of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is 22019-49-4.
Q: What is the melting point of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: Melting point of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is 86-89ºC.
Q: What are the upstream materials of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: Related upstream materials(CAS) of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone: 5465-65-6.
Q: What is the LogP of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: LogP of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is 3.34900.
Q: What is the SMILES notation of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: SMILES notation of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is O=C(CBr)c1ccc(Cl)c([N+](=O)[O-])c1.
Q: What is the safety information for 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: Safety information for 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone: 22-24/25.
Q: What is the boiling point of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone?
A: Boiling point of 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone is 336.1ºC at 760mmHg.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.