Tricarbonyldichlororuthenium(II) dimer
Tricarbonyldichlororuthenium(II) dimer structure
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Common Name | Tricarbonyldichlororuthenium(II) dimer | ||
|---|---|---|---|---|
| CAS Number | 22594-69-0 | Molecular Weight | 512.01300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6Cl4O6Ru2 | Melting Point | 208ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Tricarbonyldichlororuthenium(II) dimerTricarbonyldichlororuthenium(II) dimer is a pharmacological donor of CO releasing. CO releases from Tricarbonyldichlororuthenium(II) dimer prevents gastric mucosal oxidative damage induced by ischemia/reperfusion (I/R) improving gastric blood flow (GBF), decreasing DNA oxidation and inflammatory response on systemic level[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | carbon monoxide,dichlororuthenium |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Tricarbonyldichlororuthenium(II) dimer is a pharmacological donor of CO releasing. CO releases from Tricarbonyldichlororuthenium(II) dimer prevents gastric mucosal oxidative damage induced by ischemia/reperfusion (I/R) improving gastric blood flow (GBF), decreasing DNA oxidation and inflammatory response on systemic level[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Melting Point | 208ºC (dec.) |
|---|---|
| Molecular Formula | C6Cl4O6Ru2 |
| Molecular Weight | 512.01300 |
| Exact Mass | 511.65400 |
| LogP | 1.51000 |
| Appearance of Characters | crystal | off-white |
| InChIKey | JYHHJVKGDCZCCL-UHFFFAOYSA-J |
| SMILES | Cl[Ru]Cl.Cl[Ru]Cl.[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+] |
| Water Solubility | Insoluble in water |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332-H315-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22-36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | UN3466 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 6.1 |
This table records publicly available preparation methods, process key points and operation references.
This table lists relevant public references with title, journal and publication metadata for this compound.
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The CO donor CORM-2 inhibits LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts.
Br. J. Pharmacol. 171(12) , 2993-3009, (2014) Infection with Gram-negative bacteria has been recognized as an initiator of rheumatoid arthritis, which is characterized by chronic inflammation and infiltration of immune cells. Carbon monoxide (CO)... |
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Curcumin-induced heme oxygenase-1 expression prevents H2O2-induced cell death in wild type and heme oxygenase-2 knockout adipose-derived mesenchymal stem cells.
Int. J. Mol. Sci. 15(10) , 17974-99, (2014) Mesenchymal stem cell (MSC) administration is a promising adjuvant therapy to treat tissue injury. However, MSC survival after administration is often hampered by oxidative stress at the site of injur... |
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Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels.
J. Biol. Chem. 289(52) , 36150-7, (2014) Hemichannels (HCs) are hexamers of connexins that can form gap-junction channels at points of cell contacts or "free HCs" at non-contacting regions. HCs are involved in paracrine and autocrine cell si... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00011528 |
| corm-2 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of carbon monoxide,dichlororuthenium? |
| A: Molecular weight of carbon monoxide,dichlororuthenium is 512.01300. |
| Q: How is the water solubility of carbon monoxide,dichlororuthenium? |
| A: Water solubility of carbon monoxide,dichlororuthenium: Insoluble in water. |
| Q: What is the SMILES notation of carbon monoxide,dichlororuthenium? |
| A: SMILES notation of carbon monoxide,dichlororuthenium is Cl[Ru]Cl.Cl[Ru]Cl.[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+]. |
| Q: What is the molecular formula of carbon monoxide,dichlororuthenium? |
| A: Molecular formula of carbon monoxide,dichlororuthenium is C6Cl4O6Ru2. |
| Q: What is the InChIKey of carbon monoxide,dichlororuthenium? |
| A: InChIKey of carbon monoxide,dichlororuthenium is JYHHJVKGDCZCCL-UHFFFAOYSA-J. |
| Q: What is the LogP of carbon monoxide,dichlororuthenium? |
| A: LogP of carbon monoxide,dichlororuthenium is 1.51000. |
| Q: What is the physical appearance of carbon monoxide,dichlororuthenium? |
| A: carbon monoxide,dichlororuthenium appears as crystal | off-white. |
| Q: What is the safety information for carbon monoxide,dichlororuthenium? |
| A: Safety information for carbon monoxide,dichlororuthenium: S24/25. |
| Q: What are the uses of carbon monoxide,dichlororuthenium? |
| A: Main uses of carbon monoxide,dichlororuthenium: Tricarbonyldichlororuthenium(II) dimer is a pharmacological donor of CO releasing. CO releases from Tricarbonyldichlororuthenium(II) dimer prevents gastric mucosal oxidative damage induced by ischemia/reperfusion (I/R) improving gastric blood flow (GBF), decreasing DNA oxidation and inflammatory response on systemic level[1]. |
| Q: What is the CAS number of carbon monoxide,dichlororuthenium? |
| A: CAS number of carbon monoxide,dichlororuthenium is 22594-69-0. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |