4-(2-Thienyl)-1,3-thiazol-2-amine
4-(2-Thienyl)-1,3-thiazol-2-amine structure
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Common Name | 4-(2-Thienyl)-1,3-thiazol-2-amine | ||
|---|---|---|---|---|
| CAS Number | 28989-50-6 | Molecular Weight | 182.266 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 366.6±17.0 °C at 760 mmHg | |
| Molecular Formula | C7H6N2S2 | Melting Point | 127-130℃ | |
| MSDS | N/A | Flash Point | 175.5±20.9 °C | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-thiophen-2-yl-1,3-thiazol-2-amine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 366.6±17.0 °C at 760 mmHg |
| Melting Point | 127-130℃ |
| Molecular Formula | C7H6N2S2 |
| Molecular Weight | 182.266 |
| Flash Point | 175.5±20.9 °C |
| Exact Mass | 181.997238 |
| PSA | 95.39000 |
| LogP | 1.94 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.700 |
| InChIKey | XRNPDKQNHIKARG-UHFFFAOYSA-N |
| SMILES | Nc1nc(-c2cccs2)cs1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| HS Code | 2934999090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~%
4-(2-Thienyl)-1... CAS#:28989-50-6 |
| Literature: Zhu, Yan-Ping; Yuan, Jing-Jing; Zhao, Qin; Lian, Mi; Gao, Qing-He; Liu, Mei-Cai; Yang, Yan; Wu, An-Xin Tetrahedron, 2012 , vol. 68, # 1 p. 173 - 178 |
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~%
4-(2-Thienyl)-1... CAS#:28989-50-6 |
| Literature: Patra,M. et al. Journal of the Indian Chemical Society, 1974 , vol. 51, p. 1031 - 1034 |
|
~96%
4-(2-Thienyl)-1... CAS#:28989-50-6 |
| Literature: Farag, Ahmed M.; Hassaneen, Hamdi M.; Abbas, Ikhlas M.; Shawali, Ahmad S.; Algharib, Mohamad S. Phosphorus and Sulfur and the Related Elements, 1988 , vol. 40, p. 243 - 250 |
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~%
4-(2-Thienyl)-1... CAS#:28989-50-6 |
| Literature: Zhu, Yan-Ping; Yuan, Jing-Jing; Zhao, Qin; Lian, Mi; Gao, Qing-He; Liu, Mei-Cai; Yang, Yan; Wu, An-Xin Tetrahedron, 2012 , vol. 68, # 1 p. 173 - 178 |
|
~%
4-(2-Thienyl)-1... CAS#:28989-50-6 |
| Literature: Khanna, Mahavir S.; Garg, Chandra P.; Kapoor, Ram P. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 3 p. 364 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-(2-Thienyl)-1,3-thiazol-2-amine |
| 4-Thiophen-2-yl-thiazol-2-ylamine |
| 2-Amino-4-(2-thienyl)thiazole |
| MFCD00457532 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: Melting point of 4-thiophen-2-yl-1,3-thiazol-2-amine is 127-130℃. |
| Q: What is the English name of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: The English name of 4-thiophen-2-yl-1,3-thiazol-2-amine is 4-thiophen-2-yl-1,3-thiazol-2-amine. |
| Q: What is the LogP of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: LogP of 4-thiophen-2-yl-1,3-thiazol-2-amine is 1.94. |
| Q: What is the polar surface area (PSA) of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: Polar surface area (PSA) of 4-thiophen-2-yl-1,3-thiazol-2-amine is 95.39000. |
| Q: What English synonyms does 4-thiophen-2-yl-1,3-thiazol-2-amine have? |
| A: English synonyms of 4-thiophen-2-yl-1,3-thiazol-2-amine: 4-(2-Thienyl)-1,3-thiazol-2-amine, 4-Thiophen-2-yl-thiazol-2-ylamine, 2-Amino-4-(2-thienyl)thiazole, MFCD00457532. |
| Q: What is the molecular formula of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: Molecular formula of 4-thiophen-2-yl-1,3-thiazol-2-amine is C7H6N2S2. |
| Q: What is the CAS number of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: CAS number of 4-thiophen-2-yl-1,3-thiazol-2-amine is 28989-50-6. |
| Q: What is the InChIKey of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: InChIKey of 4-thiophen-2-yl-1,3-thiazol-2-amine is XRNPDKQNHIKARG-UHFFFAOYSA-N. |
| Q: What are the upstream materials of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: Related upstream materials(CAS) of 4-thiophen-2-yl-1,3-thiazol-2-amine: 55984-19-5;88-15-3;10531-41-6;81447-27-0. |
| Q: What is the molecular weight of 4-thiophen-2-yl-1,3-thiazol-2-amine? |
| A: Molecular weight of 4-thiophen-2-yl-1,3-thiazol-2-amine is 182.266. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |