ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate
ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate structure
|
Common Name | ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate | ||
|---|---|---|---|---|
| CAS Number | 37572-24-0 | Molecular Weight | 277.33900 | |
| Density | 1.233g/cm3 | Boiling Point | 479.5ºC at 760mmHg | |
| Molecular Formula | C14H15NO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 243.8ºC | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.233g/cm3 |
|---|---|
| Boiling Point | 479.5ºC at 760mmHg |
| Molecular Formula | C14H15NO3S |
| Molecular Weight | 277.33900 |
| Flash Point | 243.8ºC |
| Exact Mass | 277.07700 |
| PSA | 89.79000 |
| LogP | 3.76380 |
| Index of Refraction | 1.596 |
| InChIKey | ZEMJHAZGTAILJN-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1sc(-c2ccc(OC)cc2)cc1N |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934999090 |
|---|
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~32%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: Migianu, Evelyne; Kirsch, Gilbert Synthesis, 2002 , # 8 p. 1096 - 1100 |
|
~65%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: KTB Tumorforschungsgesellschaft mbH; Kubbutat, Michael, Dr.; Schächtele, Christoph, Dr.; Ehlert, Jan, Dr.; Totzke, Frank, Dr.; Kunick, Conrad, Dr.; Wölfel, Sebastian; Weber, Holger, Dr. Patent: EP2733146 A1, 2014 ; Location in patent: Page/Page column ; |
|
~65%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: Shastin; Golubinskii; Lenkova; Balenkova; Nenaidenko Russian Journal of Organic Chemistry, 2006 , vol. 42, # 2 p. 238 - 240 |
|
~%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: Migianu, Evelyne; Kirsch, Gilbert Synthesis, 2002 , # 8 p. 1096 - 1100 |
|
~%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: Migianu, Evelyne; Kirsch, Gilbert Synthesis, 2002 , # 8 p. 1096 - 1100 |
|
~%
ethyl 3-amino-5... CAS#:37572-24-0 |
| Literature: Migianu, Evelyne; Kirsch, Gilbert Synthesis, 2002 , # 8 p. 1096 - 1100 |
![N-[3-chloro-3-(4-methoxyphenyl)prop-2-enylidene]hydroxylamine structure](https://image.chemsrc.com/caspic/468/72806-45-2.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
|---|---|
| DownStream 2 | |
![4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidine structure](https://image.chemsrc.com/caspic/183/869709-83-1.png)
CAS#:869709-83-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
|
Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
|
|
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
|
|
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
|
|
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
|
|
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
|
|
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
|
|
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
|
|
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3-amino-5-(4-methoxy-phenyl)-thiophene-2-carboxylic acid ethyl ester |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: CAS number of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is 37572-24-0. |
| Q: What is the boiling point of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: Boiling point of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is 479.5ºC at 760mmHg. |
| Q: What is the LogP of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: LogP of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is 3.76380. |
| Q: What are the downstream products of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: Related downstream products(CAS) of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate: 161891-26-5;869709-83-1. |
| Q: What is the molecular formula of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: Molecular formula of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is C14H15NO3S. |
| Q: What is the InChIKey of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: InChIKey of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is ZEMJHAZGTAILJN-UHFFFAOYSA-N. |
| Q: What is the SMILES notation of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: SMILES notation of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is CCOC(=O)c1sc(-c2ccc(OC)cc2)cc1N. |
| Q: What is the molecular weight of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: Molecular weight of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is 277.33900. |
| Q: What is the polar surface area (PSA) of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: Polar surface area (PSA) of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is 89.79000. |
| Q: What is the English name of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate? |
| A: The English name of ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate is ethyl 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylate. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |