8CN
8CN structure
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Common Name | 8CN | ||
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| CAS Number | 40106-14-7 | Molecular Weight | 206.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H14N2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 8CN8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis[1]. |
Summary: 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile (CAS: 40106-14-7, molecular formula: C11H14N2S, molecular weight: 206.31), For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile |
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This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis[1]. |
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| Related Catalog | |
| In Vitro | 8CN (72 h) 对亚马逊利什曼原虫的两种进化形式(无鞭毛体和前鞭毛体)具有抗利什曼病活性，IC50 值分别为 9.8 和 1.2 μM[1]。 |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C11H14N2S |
|---|---|
| Molecular Weight | 206.31 |
| Exact Mass | 206.08800 |
| PSA | 78.05000 |
| LogP | 3.44218 |
| InChIKey | FFMNIWGELAUZIJ-UHFFFAOYSA-N |
| SMILES | N#Cc1c(N)sc2c1CCCCCC2 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934999090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
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| DownStream 1 | |
![2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide structure](https://image.chemsrc.com/caspic/493/40106-15-8.png)
CAS#:40106-15-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Specificity screen against TRPC6 for compounds that activate transient receptor poten...
Source: Johns Hopkins Ion Channel Center
Target: short transient receptor potential channel 6 [Mus musculus]
External Id: TRPC4_AG_Counter_C6
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Specificity screen against TRPC6 for compounds that inhibit transient receptor potent...
Source: Johns Hopkins Ion Channel Center
Target: short transient receptor potential channel 6 [Mus musculus]
External Id: TRPC4_Inh_Counter_C6
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Related downstream products(CAS) of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile: 40106-15-8. |
| Q: What is the InChIKey of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: InChIKey of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is FFMNIWGELAUZIJ-UHFFFAOYSA-N. |
| Q: What is the English name of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: The English name of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile. |
| Q: What are the uses of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Main uses of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile: 8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis[1]. |
| Q: What is the polar surface area (PSA) of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Polar surface area (PSA) of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is 78.05000. |
| Q: What are the upstream materials of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Related upstream materials(CAS) of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile: 502-49-8;109-77-3. |
| Q: What is the molecular weight of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Molecular weight of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is 206.31. |
| Q: What is the SMILES notation of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: SMILES notation of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is N#Cc1c(N)sc2c1CCCCCC2. |
| Q: What is the CAS number of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: CAS number of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is 40106-14-7. |
| Q: What is the molecular formula of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile? |
| A: Molecular formula of 2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile is C11H14N2S. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |