4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine
![4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine Structure](https://image.chemsrc.com/caspic/164/40493-18-3.png)
4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine structure
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Common Name | 4-Chloro-5,6,7,8-Tetrahydrobenzo[4,5]Thieno[2,3-D]Pyrimidine | ||
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| CAS Number | 40493-18-3 | Molecular Weight | 224.710 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 377.2±37.0 °C at 760 mmHg | |
| Molecular Formula | C10H9ClN2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 181.9±26.5 °C | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 377.2±37.0 °C at 760 mmHg |
| Molecular Formula | C10H9ClN2S |
| Molecular Weight | 224.710 |
| Flash Point | 181.9±26.5 °C |
| Exact Mass | 224.017502 |
| PSA | 54.02000 |
| LogP | 3.48 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.688 |
| InChIKey | PRNJDUCSVXTOTN-UHFFFAOYSA-N |
| SMILES | Clc1ncnc2sc3c(c12)CCCC3 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934999090 |
|---|
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~48%
4-Chloro-5,6,7,... CAS#:40493-18-3
Learn More
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| Literature: Yamaguchi, Hitoshi; Ishikawa, Fumiyoshi Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 326 - 332 |
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4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Nirogi, Ramakrishna V.S.; Kambhampati, Sastri Rama; Kothmirkar, Prabhakar; Arepalli, Sobhanadri; Pamuleti, Narasimha Reddy G.; Shinde, Anil K.; Dubey Synthetic Communications, 2011 , vol. 41, # 19 p. 2835 - 2851 |
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4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: NIMBUS IRIS, INC.; ROMERO, Donna L.; WESSEL, Matthew David; ROBINSON, Shaughnessy; GREENWOOD, Jeremy Robert; WATTS, Karl Shawn; FRYE, Leah Lynn; HARRIMAN, Geraldine C.; CORIN, Alan Franklin; MASSE, Craig Patent: WO2012/97013 A1, 2012 ; WO 2012/097013 A1 |
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4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Miyashita, Akira; Fujimoto, Katsuhiro; Okada, Tomomi; Higashino, Takeo Heterocycles, 1996 , vol. 42, # 2 p. 691 - 699 |
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~%
4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Yamaguchi, Hitoshi; Ishikawa, Fumiyoshi Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 326 - 332 |
|
~%
4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Yamaguchi, Hitoshi; Ishikawa, Fumiyoshi Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 326 - 332 |
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~0%
4-Chloro-5,6,7,... CAS#:40493-18-3
Detail
Learn More
|
| Literature: Yamaguchi, Hitoshi; Ishikawa, Fumiyoshi Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 326 - 332 |
|
~%
4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Jain, Kishor S.; Khedkar, Vijay M.; Arya, Nikhilesh; Rane, Prasad V.; Chaskar, Pratip K.; Coutinho, Evans C. European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 166 - 175 |
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~97%
4-Chloro-5,6,7,... CAS#:40493-18-3 |
| Literature: Perspicace, Enrico; Hesse, Stephanie; Kirsch, Gilbert; Yemloul, Mehdi; Lecomte, Claude Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 3 p. 459 - 464 |
![4-chloro-2-mesyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine structure](https://image.chemsrc.com/caspic/075/81766-01-0.png)
![5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine structure](https://www.chemsrc.com/extcaspic/201/40277-26-7.png)
![ETHYL 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE structure](https://image.chemsrc.com/caspic/045/4506-71-2.png)
![2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide structure](https://image.chemsrc.com/caspic/059/4815-28-5.png)
![4-chloro-2-methylthio-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine structure](https://image.chemsrc.com/caspic/272/81765-98-2.png)
![5,6,7,8-tetrahydro-2-(methylthio)[1]benzothieno[2,3-d]pyrimidin-4(1H)-one structure](https://image.chemsrc.com/caspic/191/51550-17-5.png)
![4-chloro-2-methylsulfinyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine structure](https://image.chemsrc.com/caspic/123/81766-00-9.png)
![4-Methylsulfanyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine structure](https://www.chemsrc.com/extcaspic/477/40277-41-6.png)
![[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one,5,6,7,8-tetrahydro structure](https://image.chemsrc.com/caspic/380/14346-24-8.png)
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: A screen for compounds that inhibit cell wall-associated teichoic acid synthesis in S...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS704
|
|
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
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|
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
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|
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: Alphascreen assay for small molecules abrogating mHTT-CaM Interaction
Source: 24983
Target: Huntingtin
External Id: KUHTS-Muma KU-CaM-Htt INH-01
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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Chloro-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine |
| 4-chloro-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine |
| 4-Chloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: The English name of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine. |
| Q: What is the polar surface area (PSA) of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: Polar surface area (PSA) of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 54.02000. |
| Q: What English synonyms does 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine have? |
| A: English synonyms of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine: 4-Chloro-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine, 4-chloro-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine, 4-Chloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine. |
| Q: What is the LogP of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: LogP of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 3.48. |
| Q: What is the InChIKey of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: InChIKey of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is PRNJDUCSVXTOTN-UHFFFAOYSA-N. |
| Q: What is the molecular weight of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: Molecular weight of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 224.710. |
| Q: What is the molecular formula of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: Molecular formula of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is C10H9ClN2S. |
| Q: What is the boiling point of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: Boiling point of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 377.2±37.0 °C at 760 mmHg. |
| Q: What is the CAS number of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: CAS number of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is 40493-18-3. |
| Q: What is the SMILES notation of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine? |
| A: SMILES notation of 4-Chloro-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidine is Clc1ncnc2sc3c(c12)CCCC3. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |