Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction

…, RS Kambhampati, P Kothmirkar, S Arepalli…

Index: Nirogi, Ramakrishna V.S.; Kambhampati, Sastri Rama; Kothmirkar, Prabhakar; Arepalli, Sobhanadri; Pamuleti, Narasimha Reddy G.; Shinde, Anil K.; Dubey Synthetic Communications, 2011 , vol. 41, # 19 p. 2835 - 2851

Full Text: HTML

Citation Number: 13

Abstract

Abstract Several functionalized thienopyrimidines were synthesized by a facile synthetic method, which includes Gewald's reaction, and were characterized by spectral and analytical data. These functionalized thienopyrimidines were converted to various new chemical entities of biological importance, such as 2-piperazinymethyl thienopyrimidines (6, 8), 4-dimethylaminoethoxy thienopyrimidines (11), and 3-dimethylaminoethyl ...