2-Methyl-6-methoxypyridine-3-boronic acid

Modify Date: 2026-07-16 21:13:07

2-Methyl-6-methoxypyridine-3-boronic acid Structure
2-Methyl-6-methoxypyridine-3-boronic acid structure
Common Name 2-Methyl-6-methoxypyridine-3-boronic acid
CAS Number 459856-12-3 Molecular Weight 166.970
Density 1.2±0.1 g/cm3 Boiling Point 318.9±52.0 °C at 760 mmHg
Molecular Formula C7H10BNO3 Melting Point N/A
MSDS USA Flash Point 146.7±30.7 °C

Summary: 2-Methyl-6-methoxypyridine-3-boronic acid, also known as (6-methoxy-2-methylpyrid-3-yl)boronic acid, has a CAS number of 459856-12-3. Its molecular formula is C7H10BNO3 and molecular weight is 166.970. This compound is a white to off-white powder with a boiling point of 318.9±52.0 °C at 760 mmHg and a density of 1.2±0.1 g/cm3. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-Methyl-6-methoxypyridine-3-boronic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 318.9±52.0 °C at 760 mmHg
Molecular Formula C7H10BNO3
Molecular Weight 166.970
Flash Point 146.7±30.7 °C
Exact Mass 167.075378
PSA 62.58000
LogP 1.15
Appearance of Characters Powder | White to off-white
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.520
InChIKey CWXWIICBKIHZFC-UHFFFAOYSA-N
SMILES COc1ccc(B(O)O)c(C)n1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 2-Methyl-6-methoxypyridine-3-boronic acid
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H318:Causes serious eye damage
H335:May cause respiratory irritation
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:2-Methyl-6-methoxypyridine-3-boronic acid
CAS number:459856-12-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, under −20◦C.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
No data
Boiling point:
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C7H10BNO3
Molecular weight: 167.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
Risk Phrases 37/38-41
Safety Phrases 26-39
HS Code 2933399090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~%

2-Methyl-6-methoxypyridine-3-boronic acid Structure

2-Methyl-6-meth...

CAS#:459856-12-3

Learn More
Literature: Eisai RandD Management Co., Ltd. Patent: EP1847535 A1, 2007 ; Location in patent: Page/Page column 123-124 ; EP 1847535 A1

~%

2-Methyl-6-methoxypyridine-3-boronic acid Structure

2-Methyl-6-meth...

CAS#:459856-12-3

Learn More
Literature: Gilligan, Paul J. Patent: US2003/125330 A1, 2003 ; US 20030125330 A1

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  2

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(6-methoxy-2-methylpyridin-3-yl)boronic acid
(6-Methoxy-2-methyl-3-pyridinyl)boronic acid
2-Methyl-6-methoxypyridine-3-boronic acid

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the safety information for 2-Methyl-6-methoxypyridine-3-boronic acid?
A: Safety information for 2-Methyl-6-methoxypyridine-3-boronic acid: 26-39.
Q: What is the LogP of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: LogP of 2-Methyl-6-methoxypyridine-3-boronic acid is 1.15.
Q: What is the InChIKey of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: InChIKey of 2-Methyl-6-methoxypyridine-3-boronic acid is CWXWIICBKIHZFC-UHFFFAOYSA-N.
Q: What is the boiling point of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: Boiling point of 2-Methyl-6-methoxypyridine-3-boronic acid is 318.9±52.0 °C at 760 mmHg.
Q: What is the molecular formula of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: Molecular formula of 2-Methyl-6-methoxypyridine-3-boronic acid is C7H10BNO3.
Q: What is the SMILES notation of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: SMILES notation of 2-Methyl-6-methoxypyridine-3-boronic acid is COc1ccc(B(O)O)c(C)n1.
Q: What are the upstream materials of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: Related upstream materials(CAS) of 2-Methyl-6-methoxypyridine-3-boronic acid: 126717-59-7;5419-55-6.
Q: What is the physical appearance of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: 2-Methyl-6-methoxypyridine-3-boronic acid appears as Powder | White to off-white.
Q: What is the polar surface area (PSA) of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: Polar surface area (PSA) of 2-Methyl-6-methoxypyridine-3-boronic acid is 62.58000.
Q: What is the CAS number of 2-Methyl-6-methoxypyridine-3-boronic acid?
A: CAS number of 2-Methyl-6-methoxypyridine-3-boronic acid is 459856-12-3.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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