Cyclo(Gly-Tyr)

Modify Date: 2026-07-01 19:01:20

Cyclo(Gly-Tyr) Structure
Cyclo(Gly-Tyr) structure
Common Name Cyclo(Gly-Tyr)
CAS Number 5845-66-9 Molecular Weight 220.225
Density 1.3±0.1 g/cm3 Boiling Point 623.1±45.0 °C at 760 mmHg
Molecular Formula C11H12N2O3 Melting Point 240ºC
MSDS N/A Flash Point 330.7±28.7 °C

 Use of Cyclo(Gly-Tyr)


Cyclo(Gly-Tyr) is a cyclic dipeptide[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione
Synonym More Synonyms

 Cyclo(Gly-Tyr) Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Cyclo(Gly-Tyr) is a cyclic dipeptide[1].
Related Catalog
References

[1]. Takashi Mizuma, et al. Uptake of Cyclic Dipeptide by PEPT1 in Caco-2 Cells: Phenolic Hydroxyl Group of Substrate Enhances Affinity for PEPT1. J Pharm Pharmacol. 2002 Sep;54(9):1293-6.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.3±0.1 g/cm3
Boiling Point 623.1±45.0 °C at 760 mmHg
Melting Point 240ºC
Molecular Formula C11H12N2O3
Molecular Weight 220.225
Flash Point 330.7±28.7 °C
Exact Mass 220.084793
PSA 78.43000
LogP -1.11
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.586
InChIKey QHLSAVHDWSYPEP-VIFPVBQESA-N
SMILES O=C1CNC(=O)C(Cc2ccc(O)cc2)N1

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

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Cyclo(Gly-Tyr) Structure

Cyclo(Gly-Tyr)

CAS#:5845-66-9

Learn More
Literature: Chemical and Pharmaceutical Bulletin, , vol. 29, # 1 p. 233 - 237

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Cyclo(Gly-Tyr) Structure

Cyclo(Gly-Tyr)

CAS#:5845-66-9

Learn More
Literature: Chemical and Pharmaceutical Bulletin, , vol. 29, # 1 p. 233 - 237

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Cyclo(Gly-Tyr) Structure

Cyclo(Gly-Tyr)

CAS#:5845-66-9

Learn More
Literature: Phytochemistry (Elsevier), , vol. 29, # 5 p. 1661 - 1665

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Cyclo(Gly-Tyr) Structure

Cyclo(Gly-Tyr)

CAS#:5845-66-9

Learn More
Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 218 - 220

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Cyclo(-Gly-Tyr)
Cyclic(glycyl-L-tyrosyl)
(S)-3-(4-hydroxy-benzyl)-piperazine-2,5-dione
3-(4-hydroxybenzyl)piperazine-2,5-dione
(3S)-3-(4-Hydroxybenzyl)-2,5-piperazinedione
Cyclo(L-tyrosylglycine)
Cyclo(glycyl-l-tyrosyl)
cyclo-(glycyl-L-tyrosyl)
cyclo-(Gly-L-Tyr)
(S)-3-(4-Hydroxy-benzyl)-piperazin-2,5-dion
3-(S)-(4-Hydroxybenzyl)piperazine-2,5-dione

 Cyclo(Gly-Tyr) | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the InChIKey of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: InChIKey of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is QHLSAVHDWSYPEP-VIFPVBQESA-N.
Q: What is the LogP of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: LogP of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is -1.11.
Q: What is the polar surface area (PSA) of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: Polar surface area (PSA) of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is 78.43000.
Q: What is the molecular weight of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: Molecular weight of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is 220.225.
Q: What is the English name of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: The English name of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione.
Q: What are the uses of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: Main uses of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione: Cyclo(Gly-Tyr) is a cyclic dipeptide[1].
Q: What English synonyms does 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione have?
A: English synonyms of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione: Cyclo(-Gly-Tyr), Cyclic(glycyl-L-tyrosyl), (S)-3-(4-hydroxy-benzyl)-piperazine-2,5-dione, 3-(4-hydroxybenzyl)piperazine-2,5-dione, (3S)-3-(4-Hydroxybenzyl)-2,5-piperazinedione, Cyclo(L-tyrosylglycine), Cyclo(glycyl-l-tyrosyl), cyclo-(glycyl-L-tyrosyl), cyclo-(Gly-L-Tyr), (S)-3-(4-Hydroxy-benzyl)-piperazin-2,5-dion, 3-(S)-(4-Hydroxybenzyl)piperazine-2,5-dione.
Q: What is the boiling point of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: Boiling point of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is 623.1±45.0 °C at 760 mmHg.
Q: What is the molecular formula of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: Molecular formula of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is C11H12N2O3.
Q: What is the SMILES notation of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione?
A: SMILES notation of 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione is O=C1CNC(=O)C(Cc2ccc(O)cc2)N1.

 Cyclo(Gly-Tyr)factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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