Rhodamine 123
Rhodamine 123 structure
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Common Name | Rhodamine 123 | ||
|---|---|---|---|---|
| CAS Number | 62669-70-9 | Molecular Weight | 380.824 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H17ClN2O3 | Melting Point | 235 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Rhodamine 123Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm). |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | rhodamine 123 |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm). |
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| Related Catalog | |
| In Vitro | The intensity of R123 fluorescence has a peak at concentration of 50 μM, and decreases to zero at higher concentrations due to self-quenching[1]. |
| Kinase Assay | Measurements are made at room temperature with continuous stirring of the mitochondrial suspension using spectrophotometer equipped with a magnetic stirrer with fluorescent cation R123 as probe. Excitation and emission wavelengths are 503 nm and 527 nm, respectively. The incubation medium is the respiration buffer. R123 and sodium pyruvate are added to final concentrations of 50 nM and 10 mM, respectively. Isolated mitochondria maintain a steady membrane potential (±5%) throughout the duration of the recording[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Melting Point | 235 °C |
|---|---|
| Molecular Formula | C21H17ClN2O3 |
| Molecular Weight | 380.824 |
| Exact Mass | 380.092773 |
| PSA | 89.31000 |
| LogP | 5.53580 |
| InChIKey | SEXIURXGNASJRB-UHFFFAOYSA-N |
| SMILES | COC(=O)c1ccccc1-c1c2ccc(=N)cc-2oc2cc(N)ccc12.Cl.O |
| Water Solubility | Partially soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | ZE0883000 |
| HS Code | 2932999099 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
|---|---|
| DownStream 4 | |
CAS#:67-56-1
CAS#:13558-31-1
CAS#:109244-59-9
CAS#:109244-61-3
CAS#:109282-63-5
CAS#:109244-58-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Protective effect of carboxymethylated chitosan on hydrogen peroxide-induced apoptosis in nucleus pulposus cells.
Mol. Med. Report. 11(3) , 1629-38, (2014) Although the etiology of intervertebral disc degeneration is poorly understood, one approach to prevent this process may be to inhibit apoptosis. In the current study, the anti‑apoptotic effects of ca... |
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Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion.
Mol. Med. Report. 11(2) , 1428-34, (2014) Auranofin (Au), an inhibitor of thioredoxin reductase, is a known anti‑cancer drug. In the present study, the anti‑growth effect of Au on HeLa cervical cancer cells was examined in association with le... |
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TLR signaling modulates side effects of anticancer therapy in the small intestine.
J. Immunol. 194(4) , 1983-95, (2015) Intestinal mucositis represents the most common complication of intensive chemotherapy, which has a severe adverse impact on quality of life of cancer patients. However, the precise pathophysiology re... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| RHODAMINE METHYL ESTER CHLORIDE |
| Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (1:1) |
| 2-(6-amino-3-imino-3H-xanthen-9-yl)-methyl ester,hydrochloride |
| rh123 |
| 3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthenium chloride |
| MFCD00012664 |
| RHODAMINE 123 HYDROCHLORIDE |
| Rhodamine 123 |
| RHODAMINE 123,PURE |
| XANTHYLIUM, 3,6-DIAMINO-9-(2-(METHOXYCARBONYL)PHENYL)-, CHLORIDE |
| rhodamine 110 methyl ester |
| Rhodamine-123 |
| EINECS 263-687-8 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of rhodamine 123? |
| A: CAS number of rhodamine 123 is 62669-70-9. |
| Q: What English synonyms does rhodamine 123 have? |
| A: English synonyms of rhodamine 123: RHODAMINE METHYL ESTER CHLORIDE, Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (1:1), 2-(6-amino-3-imino-3H-xanthen-9-yl)-methyl ester,hydrochloride, rh123, 3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthenium chloride, MFCD00012664, RHODAMINE 123 HYDROCHLORIDE, Rhodamine 123, RHODAMINE 123,PURE, XANTHYLIUM, 3,6-DIAMINO-9-(2-(METHOXYCARBONYL)PHENYL)-, CHLORIDE, rhodamine 110 methyl ester, Rhodamine-123, EINECS 263-687-8. |
| Q: What is the LogP of rhodamine 123? |
| A: LogP of rhodamine 123 is 5.53580. |
| Q: What is the melting point of rhodamine 123? |
| A: Melting point of rhodamine 123 is 235 °C. |
| Q: What is the molecular formula of rhodamine 123? |
| A: Molecular formula of rhodamine 123 is C21H17ClN2O3. |
| Q: What is the InChIKey of rhodamine 123? |
| A: InChIKey of rhodamine 123 is SEXIURXGNASJRB-UHFFFAOYSA-N. |
| Q: What are the downstream products of rhodamine 123? |
| A: Related downstream products(CAS) of rhodamine 123: 109244-59-9;109244-61-3;109282-63-5;109244-58-8. |
| Q: What are the upstream materials of rhodamine 123? |
| A: Related upstream materials(CAS) of rhodamine 123: 67-56-1;13558-31-1. |
| Q: What is the SMILES notation of rhodamine 123? |
| A: SMILES notation of rhodamine 123 is COC(=O)c1ccccc1-c1c2ccc(=N)cc-2oc2cc(N)ccc12.Cl.O. |
| Q: What are the uses of rhodamine 123? |
| A: Main uses of rhodamine 123: Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |