1-benzothiophen-2-ylmethylamine

Modify Date: 2026-07-16 08:54:23

1-benzothiophen-2-ylmethylamine Structure
1-benzothiophen-2-ylmethylamine structure
Common Name 1-benzothiophen-2-ylmethylamine
CAS Number 6314-43-8 Molecular Weight 163.240
Density 1.2±0.1 g/cm3 Boiling Point 303.9±17.0 °C at 760 mmHg
Molecular Formula C9H9NS Melting Point 58ºC
MSDS N/A Flash Point 137.6±20.9 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Benzo[b]thiophen-2-ylmethanamine
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 303.9±17.0 °C at 760 mmHg
Melting Point 58ºC
Molecular Formula C9H9NS
Molecular Weight 163.240
Flash Point 137.6±20.9 °C
Exact Mass 163.045563
PSA 54.26000
LogP 3.25
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.692
InChIKey WKYFWFHTABURGB-UHFFFAOYSA-N
SMILES NCc1cc2ccccc2s1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 1-Benzothiophen-2-ylmethylamine 97% Material Safety Data Sheet
Synonym:
CAS: 6314-43-8
Section 1 - Chemical Product MSDS Name:1-Benzothiophen-2-ylmethylamine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
6314-43-8 1-Benzothiophen-2-ylmethylamine unlisted
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 6314-43-8: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 110 - 112 deg C @0.25mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H9NS
Molecular Weight: 163

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 6314-43-8 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1-Benzothiophen-2-ylmethylamine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.*
Hazard Class: 8
UN Number: 3259
Packing Group: III
IMO
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing Group: III
RID/ADR
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 6314-43-8: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 6314-43-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6314-43-8 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes C
RIDADR UN 3259
HS Code 2934999090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

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1-benzothiophen-2-ylmethylamine Structure

1-benzothiophen...

CAS#:6314-43-8

Learn More
Literature: Journal of the American Chemical Society, , vol. 74, p. 664

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1-benzothiophen-2-ylmethylamine Structure

1-benzothiophen...

CAS#:6314-43-8

Learn More
Literature: Synthetic Communications, , vol. 25, # 17 p. 2631 - 2637

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  2

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 1-benzothiophen-2-ylmethylamineBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of human LOXL2 expressed in CHO cells incubated for 2 hrs followed by 1,5-...
Source: ChEMBL
Target: Lysyl oxidase homolog 2
External Id: CHEMBL4477150
Name: Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-ev...
Source: ChEMBL
Target: Acid-sensing ion channel 3
External Id: CHEMBL1772131
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-h...
Source: ChEMBL
Target: Cytochrome P450 2A6
External Id: CHEMBL1924632
Name: Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin ...
Source: ChEMBL
Target: Cytochrome P450 2A6
External Id: CHEMBL3390302
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin ...
Source: ChEMBL
Target: Cytochrome P450 2A6
External Id: CHEMBL3390303
Name: Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu...
Source: 15621
Target: G protein-activated inward rectifier potassium channel 2
External Id: VANDERBILT_HTS_GIRK2_HPP
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-(1-Benzothiophen-2-yl)methanamine
Benzo[b]thiophene-2-methanamine
1-benzothiophen-2-ylmethylamine
Benzo[b]thiophene-2-methylamine
1-benzothiophen-2-ylmethanamine

 1-benzothiophen-2-ylmethylamine | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of Benzo[b]thiophen-2-ylmethanamine?
A: Polar surface area (PSA) of Benzo[b]thiophen-2-ylmethanamine is 54.26000.
Q: What is the InChIKey of Benzo[b]thiophen-2-ylmethanamine?
A: InChIKey of Benzo[b]thiophen-2-ylmethanamine is WKYFWFHTABURGB-UHFFFAOYSA-N.
Q: What is the molecular formula of Benzo[b]thiophen-2-ylmethanamine?
A: Molecular formula of Benzo[b]thiophen-2-ylmethanamine is C9H9NS.
Q: What is the LogP of Benzo[b]thiophen-2-ylmethanamine?
A: LogP of Benzo[b]thiophen-2-ylmethanamine is 3.25.
Q: What English synonyms does Benzo[b]thiophen-2-ylmethanamine have?
A: English synonyms of Benzo[b]thiophen-2-ylmethanamine: 1-(1-Benzothiophen-2-yl)methanamine, Benzo[b]thiophene-2-methanamine, 1-benzothiophen-2-ylmethylamine, Benzo[b]thiophene-2-methylamine, 1-benzothiophen-2-ylmethanamine.
Q: What is the CAS number of Benzo[b]thiophen-2-ylmethanamine?
A: CAS number of Benzo[b]thiophen-2-ylmethanamine is 6314-43-8.
Q: What is the molecular weight of Benzo[b]thiophen-2-ylmethanamine?
A: Molecular weight of Benzo[b]thiophen-2-ylmethanamine is 163.240.
Q: What are the upstream materials of Benzo[b]thiophen-2-ylmethanamine?
A: Related upstream materials(CAS) of Benzo[b]thiophen-2-ylmethanamine: 6314-42-7;95-15-8.
Q: What is the boiling point of Benzo[b]thiophen-2-ylmethanamine?
A: Boiling point of Benzo[b]thiophen-2-ylmethanamine is 303.9±17.0 °C at 760 mmHg.
Q: What is the English name of Benzo[b]thiophen-2-ylmethanamine?
A: The English name of Benzo[b]thiophen-2-ylmethanamine is Benzo[b]thiophen-2-ylmethanamine.

 1-benzothiophen-2-ylmethylaminefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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