4,5-dimethoxy-2-nitrophenylacetic acid

Modify Date: 2026-07-01 16:41:54

4,5-dimethoxy-2-nitrophenylacetic acid Structure
4,5-dimethoxy-2-nitrophenylacetic acid structure
Common Name 4,5-dimethoxy-2-nitrophenylacetic acid
CAS Number 73357-18-3 Molecular Weight 241.19700
Density N/A Boiling Point 433.4ºC at 760 mmHg
Molecular Formula C10H11NO6 Melting Point 206-208°C
MSDS N/A Flash Point 215.9ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Boiling Point 433.4ºC at 760 mmHg
Melting Point 206-208°C
Molecular Formula C10H11NO6
Molecular Weight 241.19700
Flash Point 215.9ºC
Exact Mass 241.05900
PSA 101.58000
LogP 1.76230
InChIKey WJPMJFUEMVXUCV-UHFFFAOYSA-N
SMILES COc1cc(CC(=O)O)c([N+](=O)[O-])cc1OC

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 2-(4 5-Dimethoxy-2-nitrophenyl)acetic acid 95+% Material Safety Data Sheet
Synonym: 4,5-Dimethoxy-2-nitrophenylacetic aci
CAS: 73357-18-3
Section 1 - Chemical Product MSDS Name:2-(4 5-Dimethoxy-2-nitrophenyl)acetic acid 95+% Material Safety Data Sheet
Synonym:4,5-Dimethoxy-2-nitrophenylacetic aci

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
73357-18-3 2-(4,5-Dimethoxy-2-nitrophenyl)acetic 95+% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 73357-18-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: pale yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H11NO6
Molecular Weight: 241

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 73357-18-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-(4,5-Dimethoxy-2-nitrophenyl)acetic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 73357-18-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 73357-18-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 73357-18-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
HS Code 2918990090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 4,5-dimethoxy-2-nitrophenylacetic acidBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Solubility of the compound in ethanol
Source: ChEMBL
Target: N/A
External Id: CHEMBL3881281
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Antimicrobial activity against Pseudomonas aeruginosa MPAO1 after 10 hrs
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL3881279
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(4,5-dimethoxy-2-nitrophenyl)acetic acid
3,4-dimethoxy-6-nitrophenylacetic acid
2-nitro-4,5-dimethoxyphenylacetic acid
(4,5-dimethoxy-2-nitrophenyl)ethanoic acid
MFCD00118466
2-(2-BROMOPHENOXY)ETHYL]DIMETHYLAMINE OXALATE

 4,5-dimethoxy-2-nitrophenylacetic acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: The English name of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid.
Q: What is the InChIKey of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: InChIKey of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is WJPMJFUEMVXUCV-UHFFFAOYSA-N.
Q: What is the molecular formula of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: Molecular formula of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is C10H11NO6.
Q: What are the downstream products of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: Related downstream products(CAS) of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid: 35241-23-7;2982-53-8;6286-64-2;6286-65-3.
Q: What is the polar surface area (PSA) of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: Polar surface area (PSA) of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is 101.58000.
Q: What English synonyms does 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid have?
A: English synonyms of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid: (4,5-dimethoxy-2-nitrophenyl)acetic acid, 3,4-dimethoxy-6-nitrophenylacetic acid, 2-nitro-4,5-dimethoxyphenylacetic acid, (4,5-dimethoxy-2-nitrophenyl)ethanoic acid, MFCD00118466, 2-(2-BROMOPHENOXY)ETHYL]DIMETHYLAMINE OXALATE.
Q: What is the safety information for 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: Safety information for 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid: S26-S36/37/39.
Q: What is the LogP of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: LogP of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is 1.76230.
Q: What is the SMILES notation of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: SMILES notation of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is COc1cc(CC(=O)O)c([N+](=O)[O-])cc1OC.
Q: What is the CAS number of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid?
A: CAS number of 2-(4,5-dimethoxy-2-nitrophenyl)acetic acid is 73357-18-3.

 4,5-dimethoxy-2-nitrophenylacetic acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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